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naftifine hydrochloride

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Overview

What is Naftin?

Naftin Cream, 1% contains the synthetic, broad-spectrum, antifungal agent naftifine hydrochloride. Naftin Cream, 1% is for topical use only.



What does Naftin look like?



What are the available doses of Naftin?

Sorry No records found.

What should I talk to my health care provider before I take Naftin?

Sorry No records found

How should I use Naftin?

Naftin Cream, 1% is indicated for the topical treatment of tinea pedis, tinea cruris and tinea corporis caused by the organisms and

A sufficient quantity of Naftin Cream, 1% should be gently massaged into the affected and surrounding skin areas once a day. The hands should be washed after application. If no clinical improvement is seen after four weeks of treatment with Naftin Cream, 1%, the patient should be re-evaluated.


What interacts with Naftin?

Naftin Cream, 1% is contraindicated in individuals who have shown hypersensitivity to any of its components.



What are the warnings of Naftin?

A Lindane Shampoo Medication Guide must be given to the patient each time Lindane Shampoo is dispensed, as required by law.


What are the precautions of Naftin?

General

Naftin Cream, 1% is for external use only. If irritation or sensitivity develops with the use of Naftin Cream, 1%, treatment should be discontinued and appropriate therapy instituted. Diagnosis of the disease should be confirmed either by direct microscopic examination of a mounting of infected tissue in a solution of potassium hydroxide or by culture on an appropriate medium.

Information for patients





      The patient should be told to:

      Carcinogenesis, mutagenesis, impairment of fertility

      Long-term animal studies to evaluate the carcinogenic potential of Naftin Cream, 1% have not been performed. and animal studies have not demonstrated any mutagenic effect or effect on fertility.

      Pregnancy

      Nursing mothers

      It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Naftin Cream, 1% is administered to a nursing woman.

      Pediatric use

      Safety and effectiveness in pediatric patients have not been established.


      What are the side effects of Naftin?

      During clinical trials with Naftin Cream, 1%, the incidence of adverse reactions was as follows: burning/stinging (6%), dryness (3%), erythema (2%), itching (2%), local irritation (2%).


      What should I look out for while using Naftin?

      Naftin Cream, 1% is contraindicated in individuals who have shown hypersensitivity to any of its components.

      Naftin Cream, 1% is for topical use only and not for ophthalmic use.


      What might happen if I take too much Naftin?

      Sorry No Records found


      How should I store and handle Naftin?

      Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature].Naftin (naftifine hydrochloride) 1% Cream is supplied in the following sizes:


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      Clinical Information

      Chemical Structure

      No Image found
      Clinical Pharmacology

      Naftifine hydrochloride is a synthetic allylamine derivative. The following data are available, but their clinical significance is unknown. Naftifine hydrochloride has been shown to exhibit fungicidal activity against a broad spectrum of organisms, including and and fungistatic activity against species, including . Naftin Cream, 1% has only been shown to be clinically effective against the disease entities listed in the section.

      Although the exact mechanism of action against fungi is not known, naftifine hydrochloride appears to interfere with sterol biosynthesis by inhibiting the enzyme squalene 2, 3-epoxidase. This inhibition of enzyme activity results in decreased amounts of sterols, especially ergosterol, and a corresponding accumulation of squalene in the cells.

      Non-Clinical Toxicology
      Naftin Cream, 1% is contraindicated in individuals who have shown hypersensitivity to any of its components.

      Naftin Cream, 1% is for topical use only and not for ophthalmic use.

      Oils may enhance absorption of lindane, therefore, patients and caregivers applying the shampoo to others should avoid using oil treatments, or oil-based hair dressings or conditioners immediately before and after applying Lindane Shampoo.

      In addition, there are many drugs that may lower the seizure threshold, and Lindane Shampoo should be prescribed with caution in patients taking these medications. Drugs that may lower the seizure threshold include, but are not limited to the following:

      During clinical trials with Naftin Cream, 1%, the incidence of adverse reactions was as follows: burning/stinging (6%), dryness (3%), erythema (2%), itching (2%), local irritation (2%).

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      Reference

      This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
      "https://dailymed.nlm.nih.gov/dailymed/"

      While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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      Professional

      Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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      Tips

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      Interactions

      Interactions

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