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NASACORT AQ

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Overview

What is NASACORT AQ?

Triamcinolone acetonide, USP, the active ingredient in NASACORT AQ Nasal Spray, is a corticosteroid with a molecular weight of 434.51 and with the chemical designation 9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone (CHFO).

NASACORT AQ Nasal Spray is a thixotropic, water-based metered-dose pump spray formulation unit containing a microcrystalline suspension of triamcinolone acetonide in an aqueous medium. Microcrystalline cellulose, carboxymethylcellulose sodium, polysorbate 80, dextrose, benzalkonium chloride, and edetate disodium are contained in this aqueous medium; hydrochloric acid or sodium hydroxide may be added to adjust the pH to a target of 5.0 within a range of 4.5 and 6.0.



What does NASACORT AQ look like?



What are the available doses of NASACORT AQ?

NASACORT AQ Nasal Spray is a metered-dose pump spray containing the active ingredient triamcinolone acetonide. Each actuation delivers 55 mcg triamcinolone acetonide from the nasal actuator after an initial priming of 5 sprays. Each 16.5 gram bottle (120 actuations) contains 9.075 mg of triamcinolone acetonide. The bottle should be discarded when the labeled-number of actuations have been reached even though the bottle is not completely empty.

What should I talk to my health care provider before I take NASACORT AQ?

NASACORT AQ should be used during pregnancy only if potential benefit justifies potential risk to fetus. ()

How should I use NASACORT AQ?

NASACORT AQ Nasal Spray is indicated for the treatment of the nasal symptoms of seasonal and perennial allergic rhinitis in adults and children 2 years of age and older.

Administer NASACORT AQ Nasal Spray by the intranasal route only. Shake NASACORT AQ Nasal Spray well before each use.


What interacts with NASACORT AQ?

Sorry No Records found


What are the warnings of NASACORT AQ?

Sorry No Records found


What are the precautions of NASACORT AQ?

Sorry No Records found


What are the side effects of NASACORT AQ?

Sorry No records found


What should I look out for while using NASACORT AQ?

NASACORT AQ should not be administered to patients with a history of hypersensitivity to triamcinolone acetonide or to any of the other ingredients of this preparation.


What might happen if I take too much NASACORT AQ?

Chronic overdosage may result in signs/symptoms of hypercorticism There are no data on the effects of acute or chronic overdosage with NASACORT AQ Nasal Spray. Because of low systemic bioavailability and an absence of acute drug-related systemic findings in clinical studies overdose is unlikely to require any therapy other than observation.

Acute overdosing with the intranasal dosage form is unlikely in view of the total amount of active ingredient present and low bioavailability of triamcinolone acetonide. In the event that the entire contents of the bottle were administered all at once, via either oral or nasal application, clinically significant systemic adverse events would most likely not result.


How should I store and handle NASACORT AQ?

Store at Controlled Room Temperature, 20 to 25°C (68 to 77°F) Tablets containing metoprolol succinate equivalent to the indicated weight of metoprolol tartrate, USP, are white, coated, and scored.abcdStore at 20°-25°C (68°-77°F). [See USP Controlled Room Temperature.]Tablets containing metoprolol succinate equivalent to the indicated weight of metoprolol tartrate, USP, are white, coated, and scored.abcdStore at 20°-25°C (68°-77°F). [See USP Controlled Room Temperature.]Tablets containing metoprolol succinate equivalent to the indicated weight of metoprolol tartrate, USP, are white, coated, and scored.abcdStore at 20°-25°C (68°-77°F). [See USP Controlled Room Temperature.]Tablets containing metoprolol succinate equivalent to the indicated weight of metoprolol tartrate, USP, are white, coated, and scored.abcdStore at 20°-25°C (68°-77°F). [See USP Controlled Room Temperature.]Tablets containing metoprolol succinate equivalent to the indicated weight of metoprolol tartrate, USP, are white, coated, and scored.abcdStore at 20°-25°C (68°-77°F). [See USP Controlled Room Temperature.]Tablets containing metoprolol succinate equivalent to the indicated weight of metoprolol tartrate, USP, are white, coated, and scored.abcdStore at 20°-25°C (68°-77°F). [See USP Controlled Room Temperature.]


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Clinical Information

Chemical Structure

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Clinical Pharmacology

Triamcinolone acetonide is a synthetic fluorinated corticosteroid with approximately 8 times the potency of prednisone in animal models of inflammation.

Although the precise mechanism of corticosteroid antiallergic action is unknown, corticosteroids have been shown to have a wide range of actions on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, cytokines) involved in inflammation.

Non-Clinical Toxicology
NASACORT AQ should not be administered to patients with a history of hypersensitivity to triamcinolone acetonide or to any of the other ingredients of this preparation.

This drug may enhance the effects of: other narcotic analgesics, alcohol, general anesthetics, tranquilizers such as chlordiazepoxide, sedative-hypnotics or other CNS depressants, causing increased CNS depression.

Epistaxis, nasal septal perforation, infection, impaired wound healing. Monitor patients periodically for signs of adverse effects on the nasal mucosa. Avoid use in patients with recent nasal septal ulcers, nasal surgery, or trauma. ()

Development of glaucoma or posterior subcapsular cataracts. Monitor patients closely with a change in vision or with a history of increased intraocular pressure, glaucoma, and/or cataracts. ()

Potential worsening of existing tuberculosis; fungal, bacterial, viral, or parasitic infections; or ocular herpes simplex. More serious or even fatal course of chickenpox or measles in susceptible patients. Use caution in patient with the above because of the potential for worsening of these infections. ()

Hypercorticism and adrenal suppression with very high dosages or at the regular dosage in susceptible individuals. If such changes occur, discontinue NASACORT AQ Nasal Spray slowly. ()

Potential reduction in growth velocity in children. Monitor growth routinely in pediatric patients receiving NASACORT AQ Nasal Spray. (, )

Systemic and local corticosteroid use may result in the following:

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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