Disclaimer:

Medidex is not a provider of medical services and all information is provided for the convenience of the user. No medical decisions should be made based on the information provided on this website without first consulting a licensed healthcare provider.This website is intended for persons 18 years or older. No person under 18 should consult this website without the permission of a parent or guardian.

Vinorelbine tartrate

×

Overview

What is NAVELBINE?

NAVELBINE (vinorelbine tartrate) is a semi-synthetic vinca alkaloid for intravenous injection. Chemically, vinorelbine tartrate is 3',4'-didehydro-4'-deoxy-C'-norvincaleukoblastine [R-(R*,R*)-2, 3-dihydroxybutanedioate (1:2)(tartrate)] and has the following structure:

CHNO•2CHO

M.W. 1079.12

NAVELBINE Injection is a sterile nonpyrogeinc aqueous solution. Each milliliter of solution contains vinorelbine tartrate equivalent to 10 mg vinorelbine in Water for Injection. The pH of NAVELBINE Injection is approximately 3.5.



What does NAVELBINE look like?



What are the available doses of NAVELBINE?

NAVELBINE Injection

Clear colorless to pale yellow solution in single use vials:

1 mL (10 mg/ 1 mL)

5 mL (50 mg/ 5 mL)

What should I talk to my health care provider before I take NAVELBINE?

Nursing Mothers: discontinue drug or nursing taking into consideration importance of drug to mother ()

How should I use NAVELBINE?

NAVELBINE is indicated:

In Combination with Cisplatin 100 mg/m

In Combination with Cisplatin 120 mg/m

Single-Agent


What interacts with NAVELBINE?

Sorry No Records found


What are the warnings of NAVELBINE?

Sorry No Records found


What are the precautions of NAVELBINE?

Sorry No Records found


What are the side effects of NAVELBINE?

Sorry No records found


What should I look out for while using NAVELBINE?

None


What might happen if I take too much NAVELBINE?

There is no known antidote for overdoses of NAVELBINE. Overdoses involving quantities up to 10 times the recommended dose (30 mg/m) have been reported. The toxicities described were consistent with those listed in the ADVERSE REACTIONS section including paralytic ileus, stomatitis, and esophagitis. Bone marrow aplasia, sepsis, and paresis have also been reported. Fatalities have occurred following overdose of NAVELBINE. If overdosage occurs, general supportive measures together with appropriate blood transfusions, growth factors, and antibiotics should be instituted as deemed necessary by the physician.


How should I store and handle NAVELBINE?

Store at 20-25°C (68-77°F). Excursions permitted to 15-30°C (59-86°F). [See USP Controlled Room Temperature.] Protect from light.Dispense in a tight, light-resistant container with a child-resistant closure.Store at 20-25°C (68-77°F). Excursions permitted to 15-30°C (59-86°F). [See USP Controlled Room Temperature.] Protect from light.Dispense in a tight, light-resistant container with a child-resistant closure.NAVELBINE Injection is a clear, colorless to pale yellow aqueous solution available in single-dose vials with royal blue caps, individually packaged in a carton as:Store the vials at 2° to 8°C (36° to 46°F) in the carton. Protect from light. DO NOT FREEZE. Unopened vials of NAVELBINE are stable at 25°C (77°F) for up to 72 hours. NAVELBINE is a cytotoxic drug. Follow applicable special handling and disposal procedures. NAVELBINE Injection is a clear, colorless to pale yellow aqueous solution available in single-dose vials with royal blue caps, individually packaged in a carton as:Store the vials at 2° to 8°C (36° to 46°F) in the carton. Protect from light. DO NOT FREEZE. Unopened vials of NAVELBINE are stable at 25°C (77°F) for up to 72 hours. NAVELBINE is a cytotoxic drug. Follow applicable special handling and disposal procedures. NAVELBINE Injection is a clear, colorless to pale yellow aqueous solution available in single-dose vials with royal blue caps, individually packaged in a carton as:Store the vials at 2° to 8°C (36° to 46°F) in the carton. Protect from light. DO NOT FREEZE. Unopened vials of NAVELBINE are stable at 25°C (77°F) for up to 72 hours. NAVELBINE is a cytotoxic drug. Follow applicable special handling and disposal procedures.