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Nedocromil Sodium

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Overview

What is Nedocromil Sodium?

Nedocromil Sodium Ophthalmic Solution, 2% is a clear, yellow, sterile solution for topical ophthalmic use.

Nedocromil sodium is represented by the following structural formula:

Chemical name:

Each mL contains: Nedocromil Sodium 20 mg/mL (2%); Benzalkonium Chloride 0.01%; Edetate Disodium 0.05%, Purified Water, and Sodium Chloride 0.5%. It has a pH of 4.0 to 5.5 and osmolality range of 270 to 330 mOsm/kg.



What does Nedocromil Sodium look like?



What are the available doses of Nedocromil Sodium?

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What should I talk to my health care provider before I take Nedocromil Sodium?

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How should I use Nedocromil Sodium?

Nedocromil Sodium Ophthalmic Solution is indicated for the treatment of itching associated with allergic conjunctivitis.

The recommended dosage is one or two drops in each eye twice a day. Nedocromil Ophthalmic Solution 2% should be used at regular intervals.

Treatment should be continued throughout the period of exposure (i.e., until the pollen season is over or until exposure to the offending allergen is terminated), even when symptoms are absent.


What interacts with Nedocromil Sodium?

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What are the warnings of Nedocromil Sodium?

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What are the precautions of Nedocromil Sodium?

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What are the side effects of Nedocromil Sodium?

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What should I look out for while using Nedocromil Sodium?

Nedocromil Sodium Ophthalmic Solution is contraindicated in those patients who have shown hypersensitivity to nedocromil sodium or to any of the other ingredients.


What might happen if I take too much Nedocromil Sodium?

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How should I store and handle Nedocromil Sodium?

Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayNedocromil Sodium Ophthalmic Solution, 2% is supplied sterile in opaque white LDPE plastic bottles with dropper tips and white polypropylene caps as follows: 5 mL in a 10 cc bottle - Nedocromil Sodium Ophthalmic Solution, 2% is supplied sterile in opaque white LDPE plastic bottles with dropper tips and white polypropylene caps as follows: 5 mL in a 10 cc bottle -


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Nedocromil sodium is a mast cell stabilizer. Nedocromil sodium inhibits the release of mediators from cells involved in hypersensitivity reactions. Decreased chemotaxis and decreased activation of eosinophils have also been demonstrated.

In vitro

Non-Clinical Toxicology
Nedocromil Sodium Ophthalmic Solution is contraindicated in those patients who have shown hypersensitivity to nedocromil sodium or to any of the other ingredients.

Patients should be advised to follow the patient instructions listed on the Information for Patients sheet.

Users of contact lenses should refrain from wearing lenses while exhibiting the signs and symptoms of allergic conjunctivitis.

Patients should be instructed to avoid allowing the tip of the dispensing container to contact the eye, surrounding structures, fingers, or any other surface in order to avoid contamination of the solution by common bacteria known to cause ocular infections. Serious damage to the eye and subsequent loss of vision may result from using contaminated solutions.

The most frequently reported adverse experience was headache (~40%). Ocular burning, irritation and stinging, unpleasant taste, and nasal congestion have been reported to occur in 10 to 30% of patients. Other events occurring between 1 to 10% included asthma, conjunctivitis, eye redness, photophobia, and rhinitis.

Some of these events were similar to the underlying ocular disease being studied.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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