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Neut Sodium Bicarbonate
Overview
What is Neut Sodium Bicarbonate?
Neut (4% sodium bicarbonate additive solution) is a sterile, nonpyrogenic solution of sodium bicarbonate in water for injection. It is administered by the intravenous route only after addition as a neutralizing agent to an acidic large volume parenteral solution. Each 5 mL contains sodium bicarbonate 0.2 g (2.4 mEq each of Na and HCO‾ ); edetate disodium, anhydrous 10 mg added as a stabilizer. Total sodium (Na) content of each 5 mL is 56.1 mg (11.2 mg/mL).
The solutions contain no bacteriostat, antimicrobial agent or added buffer; pH 8.0 (7.0 to 8.5).
Sodium Bicarbonate, USP is chemically designated as NaHCO, a white crystalline powder soluble in water.
What does Neut Sodium Bicarbonate look like?

What are the available doses of Neut Sodium Bicarbonate?
Sorry No records found.
What should I talk to my health care provider before I take Neut Sodium Bicarbonate?
Sorry No records found
How should I use Neut Sodium Bicarbonate?
Neut (4% sodium bicarbonate additive solution) is indicated for use as an additive to raise the pH of acid solutions administered intravenously to reduce the incidence of chemical phlebitis and patient discomfort due to vein irritation at or near the site of infusion.
One vial (5 mL) of Neut added to a liter (1000 mL) of any of the following Hospira parenteral solutions will increase the pH to a more physiologic range. Specific pH may vary slightly from lot to lot.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See
Addition of one vial of Neut to one-half liter (500 mL) is recommended to achieve a more physiologic pH of the following Hospira parenteral solutions:
Note:
What interacts with Neut Sodium Bicarbonate?
Not for use as a systemic alkalizer.
What are the warnings of Neut Sodium Bicarbonate?
For hospital use only if misoprostol were to be used for cervical ripening, induction of labor, or for the treatment of serious post-partum hemorrhage, which are outside of the approved indication.
What are the precautions of Neut Sodium Bicarbonate?
Do not administer unless solution is clear and seal is intact. Discard unused portion.
Solutions prepared with Neut (4% sodium bicarbonate additive solution) should be administered promptly. When introducing additives, use aseptic technique, mix thoroughly and do not store.
When Neut is added to Hospira solutions, the compatibility of these solutions with other drugs may be altered. (See section on , etc., for listing of additives tested with Neut added D5-W.)
Raising the pH of I.V. fluids with Neut will only reduce the incidence of chemical irritation caused by the infusate; it will not diminish any foreign body effects caused by the needle or catheter.
Pregnancy
Animal reproduction studies have not been conducted with sodium bicarbonate. It is also not known whether sodium bicarbonate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Sodium bicarbonate should be given to a pregnant woman only if clearly needed.
What are the side effects of Neut Sodium Bicarbonate?
None known.
What should I look out for while using Neut Sodium Bicarbonate?
Not for use as a systemic alkalizer.
None known.
What might happen if I take too much Neut Sodium Bicarbonate?
None known.
How should I store and handle Neut Sodium Bicarbonate?
Storage and HandlingStore at 20ºC-25ºC (68ºF-77ºF); excursions permitted to 15ºC- 30ºC (59ºF -86ºF) [See USP Controlled Room Temperature].Storage and HandlingStore at 20ºC-25ºC (68ºF-77ºF); excursions permitted to 15ºC- 30ºC (59ºF -86ºF) [See USP Controlled Room Temperature].Neut (sodium bicarbonate 4% additive solution), single-dose glass fliptop vialNDC 0409-6609-25: 2.4 mEq/5 mL (0.48 mEq/mL), supplied in a 5 mL partial-fill single-dose, glass fliptop vial.Neut (sodium bicarbonate 4% additive solution), single-dose glass fliptop vialNDC 0409-6609-25: 2.4 mEq/5 mL (0.48 mEq/mL), supplied in a 5 mL partial-fill single-dose, glass fliptop vial.