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NOVOLOG

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Overview

What is NOVOLOG?

NOVOLOG (insulin aspart injection) is a rapid-acting human insulin analog used to lower blood glucose. NOVOLOG is homologous with regular human insulin with the exception of a single substitution of the amino acid proline by aspartic acid in position B28, and is produced by recombinant DNA technology utilizing (baker's yeast). Insulin aspart has the empirical formula CHN0S and a molecular weight of 5825.8.

NOVOLOG is a sterile, aqueous, clear, and colorless solution, that contains insulin aspart 100 Units/mL, glycerin 16 mg/mL, phenol 1.50 mg/mL, metacresol 1.72 mg/mL, zinc 19.6 mcg/mL, disodium hydrogen phosphate dihydrate 1.25 mg/mL, sodium chloride 0.58 mg/mL and water for injection. NOVOLOG has a pH of 7.2-7.6. Hydrochloric acid 10% and/or sodium hydroxide 10% may be added to adjust pH.



What does NOVOLOG look like?



What are the available doses of NOVOLOG?

Each presentation contains 100 Units of insulin aspart per mL (U-100)

What should I talk to my health care provider before I take NOVOLOG?

How should I use NOVOLOG?

NOVOLOG is a rapid acting human insulin analog indicated to improve glycemic control in adults and children with diabetes mellitus.

Subcutaneous injection ():

o

o

o

Continuous Subcutaneous Infusion (Insulin Pump) ():

o

o

o

Intravenous Administration ()

o

o

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2.4

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2.4


What interacts with NOVOLOG?

Sorry No Records found


What are the warnings of NOVOLOG?

Sorry No Records found


What are the precautions of NOVOLOG?

Sorry No Records found


What are the side effects of NOVOLOG?

Sorry No records found


What should I look out for while using NOVOLOG?

NOVOLOG is contraindicated:


What might happen if I take too much NOVOLOG?

Excess insulin administration may cause hypoglycemia and hypokalemia . Mild episodes of hypoglycemia usually can be treated with oral glucose. Adjustments in drug dosage, meal patterns, or exercise may be needed. More severe episodes with coma, seizure, or neurologic impairment may be treated with intramuscular/subcutaneous glucagon or concentrated intravenous glucose. Sustained carbohydrate intake and observation may be necessary because hypoglycemia may recur after apparent clinical recovery. Hypokalemia must be corrected appropriately.


How should I store and handle NOVOLOG?

Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature].Product: 50090-1664NDC: 50090-1664-0 10 mL in a VIAL, GLASS Product: 50090-1665NDC: 50090-1665-0 3 mL in a CARTRIDGE Product: 50090-1678NDC: 50090-1678-0 3 mL in a SYRINGE, PLASTIC Product: 50090-1664NDC: 50090-1664-0 10 mL in a VIAL, GLASS Product: 50090-1665NDC: 50090-1665-0 3 mL in a CARTRIDGE Product: 50090-1678NDC: 50090-1678-0 3 mL in a SYRINGE, PLASTIC Product: 50090-1664NDC: 50090-1664-0 10 mL in a VIAL, GLASS Product: 50090-1665NDC: 50090-1665-0 3 mL in a CARTRIDGE Product: 50090-1678NDC: 50090-1678-0 3 mL in a SYRINGE, PLASTIC Product: 50090-1664NDC: 50090-1664-0 10 mL in a VIAL, GLASS Product: 50090-1665NDC: 50090-1665-0 3 mL in a CARTRIDGE Product: 50090-1678NDC: 50090-1678-0 3 mL in a SYRINGE, PLASTIC Product: 50090-1664NDC: 50090-1664-0 10 mL in a VIAL, GLASS Product: 50090-1665NDC: 50090-1665-0 3 mL in a CARTRIDGE Product: 50090-1678NDC: 50090-1678-0 3 mL in a SYRINGE, PLASTIC Product: 50090-1664NDC: 50090-1664-0 10 mL in a VIAL, GLASS Product: 50090-1665NDC: 50090-1665-0 3 mL in a CARTRIDGE Product: 50090-1678NDC: 50090-1678-0 3 mL in a SYRINGE, PLASTIC


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

The primary activity of insulin, including NOVOLOGis the regulation of glucose metabolism. Insulin, and its analogs lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin inhibits lipolysis and proteolysis, and enhances protein synthesis.

Non-Clinical Toxicology
NOVOLOG is contraindicated:

MAO inhibitors prolong and intensify the anticholinergic effects of antihistamines.

Antihistamines may have additive effects with alcohol and other CNS depressants, e.g., hypnotics, sedatives, tranquilizers, antianxiety agents.

NOVOLOG FlexPen, NOVOLOG FlexTouch, PenFill cartridge, and PenFill cartridge devices should never be shared between patients, even if the needle is changed. Patients using NOVOLOG vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens.

 

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

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Interactions

Interactions

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