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Nymalize

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Overview

What is Nymalize?

NYMALIZE contains nimodipine, a dihydropyridine calcium channel blocker. Nimodipine is isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(-nitrophenyl)-3,5-pyridinedicarboxylate. It has a molecular weight of 418.5 and a molecular formula of CHNO. The structural formula is:

Nimodipine is a yellow crystalline substance, practically insoluble in water.

NYMALIZE Oral Solution contains 60 mg of nimodipine per 20 mL. In addition, the oral solution contains the following inactive ingredients: ethanol, glycerin, methylparaben, polyethylene glycol 400, sodium phosphate monobasic, sodium phosphate dibasic, and water.



What does Nymalize look like?



What are the available doses of Nymalize?

Oral solution (3 mg per mL):

What should I talk to my health care provider before I take Nymalize?

How should I use Nymalize?

NYMALIZE is indicated for the improvement of neurological outcome by reducing the incidence and severity of ischemic deficits in adult patients with subarachnoid hemorrhage (SAH) from ruptured intracranial berry aneurysms regardless of their post-ictus neurological condition (i.e., Hunt and Hess Grades I-V).

Administer only enterally (e.g., oral, nasogastric tube, or gastric tube route). Do not administer intravenously or by other parenteral routes. For all routes of administration, begin NYMALIZE within 96 hours of the onset of SAH. Administer one hour before a meal or two hours after a meal for all routes of administration .


What interacts with Nymalize?

Sorry No Records found


What are the warnings of Nymalize?

Sorry No Records found


What are the precautions of Nymalize?

Sorry No Records found


What are the side effects of Nymalize?

Sorry No records found


What should I look out for while using Nymalize?

None.


What might happen if I take too much Nymalize?

There have been no reports of overdosage from the oral administration of nimodipine. Symptoms of overdosage would be expected to be related to cardiovascular effects such as excessive peripheral vasodilation with marked systemic hypotension. Clinically significant hypotension due to nimodipine overdosage may require active cardiovascular support with pressor agents and specific treatments for calcium channel blocker overdose. Since nimodipine is highly protein-bound, dialysis is not likely to be of benefit.


How should I store and handle Nymalize?

StorageStore at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature] and protect from light.StorageStore at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature] and protect from light.NYMALIZE (nimodipine) Oral Solution 3 mg/mL is a pale yellow solution and is supplied as follows: