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Olopatadine Hydrochloride

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Overview

What is Olopatadine Hydrochloride?

Olopatadine Hydrochloride Ophthalmic Solution USP, 0.2% is a sterile ophthalmic solution containing olopatadine for topical administration to the eyes. Olopatadine hydrochloride is a white to off-white, crystalline, water-soluble powder with a molecular weight of 373.88 and a molecular formula of CHNO • HCl. The chemical structure is presented below:

Chemical Name:

Each mL of Olopatadine Hydrochloride Ophthalmic Solution USP, 0.2% contains: 2.22 mg olopatadine hydrochloride equivalent to 2 mg olopatadine. povidone; sodium chloride; sodium phosphate dibasic (anhydrous); edetate disodium dihydrate; benzalkonium chloride 0.01% ();hydrochloric acid/sodium hydroxide (to adjust pH); and water for injection.

It has a pH of approximately 5.0 - 8.0 and an osmolality range of 260 - 320 mOsm/kg.



What does Olopatadine Hydrochloride look like?



What are the available doses of Olopatadine Hydrochloride?

Ophthalmic solution 0.2%: each ml contains 2.22 mg of olopatadine hydrochloride. ()

What should I talk to my health care provider before I take Olopatadine Hydrochloride?

How should I use Olopatadine Hydrochloride?

Olopatadine hydrochloride ophthalmic solution, 0.2% is indicated for the treatment of ocular itching associated with allergic conjunctivitis.

The recommended dose is one drop in each affected eye once a day.


What interacts with Olopatadine Hydrochloride?

Sorry No Records found


What are the warnings of Olopatadine Hydrochloride?

Sorry No Records found


What are the precautions of Olopatadine Hydrochloride?

Sorry No Records found


What are the side effects of Olopatadine Hydrochloride?

Sorry No records found


What should I look out for while using Olopatadine Hydrochloride?

None.


What might happen if I take too much Olopatadine Hydrochloride?

Sorry No Records found


How should I store and handle Olopatadine Hydrochloride?

Olopatadine Hydrochloride Ophthalmic Solution USP, 0.2% is supplied in a white opaque ophthalmic bottle with a white translucent ophthalmic dropper and a white opaque plastic cap in the following size:2.5 mL fill in 5 mL bottle: NDC 60505-0586-4StorageKeep out of reach of children.Olopatadine Hydrochloride Ophthalmic Solution USP, 0.2% is supplied in a white opaque ophthalmic bottle with a white translucent ophthalmic dropper and a white opaque plastic cap in the following size:2.5 mL fill in 5 mL bottle: NDC 60505-0586-4StorageKeep out of reach of children.Olopatadine Hydrochloride Ophthalmic Solution USP, 0.2% is supplied in a white opaque ophthalmic bottle with a white translucent ophthalmic dropper and a white opaque plastic cap in the following size:2.5 mL fill in 5 mL bottle: NDC 60505-0586-4StorageKeep out of reach of children.Olopatadine Hydrochloride Ophthalmic Solution USP, 0.2% is supplied in a white opaque ophthalmic bottle with a white translucent ophthalmic dropper and a white opaque plastic cap in the following size:2.5 mL fill in 5 mL bottle: NDC 60505-0586-4StorageKeep out of reach of children.


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Olopatadine is a mast cell stabilizer and a histamine H antagonist. Decreased chemotaxis and inhibition of eosinophil activation has also been demonstrated.

Non-Clinical Toxicology
None.

5.1 For topical ocular use only. Not for injection or oral use.

5.2 Contamination of Tip and Solution

As with any eye drop, to prevent contaminating the dropper tip and solution, care should be taken not to touch the eyelids or surrounding areas with the dropper tip of the bottle. Keep bottle tightly closed when not in use.

5.3 Contact Lens Use

Patients should be advised not to wear a contact lens if their eye is red.

Olopatadine hydrochloride ophthalmic solution, 0.2% should not be used to treat contact lens related irritation.

The preservative in olopatadine hydrochloride ophthalmic solution, 0.2%, benzalkonium chloride, may be absorbed by soft contact lenses. Patients who wear soft contact lenses andwhose eyes are not red,should be instructed to wait at least ten minutes after instillingolopatadine hydrochloride ophthalmic solution, 0.2%before they insert their contact lenses.

Symptoms similar to cold syndrome and pharyngitis were reported at an incidence of approximately 10%.

The following adverse experiences have been reported in 5% or less of patients:

Ocular:

Non-ocular:

Some of these events were similar to the underlying disease being studied.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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