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Bupivacaine Hydrochloride, Lidocaine Hydrochloride, Sodium Chloride, Povidone-Iodine, Isopropyl Alcohol

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Overview

What is P-Care 100MX?

Sodium Chloride Injection, USP, 0.9% is a sterile, nonpyrogenic solution. The osmolarity is 300 mOsmol per liter (calculated).

Each mL contains: Sodium chloride 9 mg; Water for Injection q.s. It contains no bacteriostat, antimicrobial agent or added buffer and is supplied only in single dose containers. Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (pH 4.5-7.0).

Sodium chloride occurs as colorless cubic crystals or white crystalline powder and has a saline taste. Sodium chloride is freely soluble in water. It is soluble in glycerin and slightly soluble in alcohol.

The empirical formula for sodium choride is NaCl and the molecular weight is 58.44.



What does P-Care 100MX look like?



What are the available doses of P-Care 100MX?

Sorry No records found.

What should I talk to my health care provider before I take P-Care 100MX?

Sorry No records found

How should I use P-Care 100MX?

Wipe injection site vigorously and discard


What interacts with P-Care 100MX?

Sorry No Records found


What are the warnings of P-Care 100MX?

Sorry No Records found


What are the precautions of P-Care 100MX?

Sorry No Records found


What are the side effects of P-Care 100MX?

Sorry No records found


What should I look out for while using P-Care 100MX?

Lidocaine HCl is contraindicated in patients with a known history of hyper sensitivity to local anesthetics of the amide type.

For External Use Only.

Flammable, keep away from fire or flame.


What might happen if I take too much P-Care 100MX?

When used as a diluent, solvent or intravascular flushing solution, this parenteral preparation is unlikely to pose a threat of sodium chloride or fluid overload except possibly in very small infants.  In the event these should occur, reevaluate the patient and institute appropriate corrective measures.  (See and ).


How should I store and handle P-Care 100MX?

Storage ConditionsSodium Chloride Injection, USP, 0.9%, preservative free, is available as follows:Single dose vials, packaged 25 vials per tray.Preservative Free.Use only if solution is clear and seal intact.Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature].*Vial stoppers do not contain natural rubber latex.45764DRevised: January 2008Sodium Chloride Injection, USP, 0.9%, preservative free, is available as follows:Single dose vials, packaged 25 vials per tray.Preservative Free.Use only if solution is clear and seal intact.Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature].*Vial stoppers do not contain natural rubber latex.45764DRevised: January 2008Sodium Chloride Injection, USP, 0.9%, preservative free, is available as follows:Single dose vials, packaged 25 vials per tray.Preservative Free.Use only if solution is clear and seal intact.Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature].*Vial stoppers do not contain natural rubber latex.45764DRevised: January 2008Sodium Chloride Injection, USP, 0.9%, preservative free, is available as follows:Single dose vials, packaged 25 vials per tray.Preservative Free.Use only if solution is clear and seal intact.Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature].*Vial stoppers do not contain natural rubber latex.45764DRevised: January 2008Sodium Chloride Injection, USP, 0.9%, preservative free, is available as follows:Single dose vials, packaged 25 vials per tray.Preservative Free.Use only if solution is clear and seal intact.Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature].*Vial stoppers do not contain natural rubber latex.45764DRevised: January 2008Sodium Chloride Injection, USP, 0.9%, preservative free, is available as follows:Single dose vials, packaged 25 vials per tray.Preservative Free.Use only if solution is clear and seal intact.Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature].*Vial stoppers do not contain natural rubber latex.45764DRevised: January 2008Sodium Chloride Injection, USP, 0.9%, preservative free, is available as follows:Single dose vials, packaged 25 vials per tray.Preservative Free.Use only if solution is clear and seal intact.Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature].*Vial stoppers do not contain natural rubber latex.45764DRevised: January 2008Sodium Chloride Injection, USP, 0.9%, preservative free, is available as follows:Single dose vials, packaged 25 vials per tray.Preservative Free.Use only if solution is clear and seal intact.Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature].*Vial stoppers do not contain natural rubber latex.45764DRevised: January 2008


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Clinical Information

Chemical Structure

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Clinical Pharmacology

Sodium chloride in water dissociates to provide sodium (Na+) and chloride (Cl—) ions. These ions are normal constituents of the body fluids (principally extracellular) and are essential for maintaining electrolyte balance.

The distribution and excretion of sodium (Na+) and chloride (Cl—)are largely under the control of the kidney which maintains a balance between intake and output.

The small volume of fluid and amount of sodium chloride provided by Sodium Chloride Injection, USP, 0.9%, when used only as a vehicle for parenteral injection of drugs, is unlikely to exert a significant effect on fluid and electrolyte balance except possibly in very small infants.

Water is an essential constituent of all body tissues and accounts for approximately 70% of total body weight. Average normal adult daily requirement ranges from two to three liters (1 to 1.5 liters each for insensible water loss by perspiration and urine production).

Water balance is maintained by various regulatory mechanisms. Water distribution depends primarily on the concentration of electrolytes in the body compartments and sodium (Na+) plays a major role in maintaining physiologic equilibrium.

Non-Clinical Toxicology
Lidocaine HCl is contraindicated in patients with a known history of hyper sensitivity to local anesthetics of the amide type.

For External Use Only.

Flammable, keep away from fire or flame.

The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors or tricyclic antidepressants may produce severe, prolonged hypertension.

Phenothiazines and butyrophenones may reduce or reverse the pressor effect of epinephrine.

Concurrent use of these agents should generally be avoided. In situations when concurrent therapy is necessary, careful patient monitoring is essential.

Concurrent administration of vasopressor drugs (for the treatment of hypotension related to obstetric blocks) and ergot-type oxytocic drugs may cause severe, persistent hypertension or cerebrovascular accidents.

General

Pregnancy

Reactions which may occur because of this solution, added drugs or the technique of reconstitution or administration include febrile response, local tenderness, abscess, tissue necrosis or infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection and extravasation.

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate countermeasures and, if possible, retrieve and save the remainder of the unused vehicle for examination.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

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Interactions

Interactions

A total of 440 drugs (1549 brand and generic names) are known to interact with Imbruvica (ibrutinib). 228 major drug interactions (854 brand and generic names) 210 moderate drug interactions (691 brand and generic names) 2 minor drug interactions (4 brand and generic names) Show all medications in the database that may interact with Imbruvica (ibrutinib).