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Methylprednisolone Acetate, Povidone-Iodine, Isopropyl Alcohol

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Overview

What is P-Care D40G?

DEPO-MEDROL is an anti-inflammatory glucocorticoid for intramuscular, intra-articular, soft tissue or intralesional injection. It is available as single-dose vials in two strengths: 40 mg/mL, 80 mg/mL.

Each mL of these preparations contains:Methylprednisolone acetate ..............................................Polyethylene glycol 3350 ..................................................29 mg .............28 mgMyristyl-gamma-picolinium chloride..............................0.195 mg .......0.189 mg

Sodium Chloride was added to adjust tonicity.

When necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid.

The pH of the finished product remains within the USP specified range (e.g., 3.0 to 7.0.)

The chemical name for methylprednisolone acetate is pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-,(6α,11β)- and the molecular weight is 416.51. The structural formula is represented below:

DEPO-MEDROL Sterile Aqueous Suspension contains methylprednisolone acetate which is the 6-methyl derivative of prednisolone. Methylprednisolone acetate is a white or practically white, odorless, crystalline powder which melts at about 215° with some decomposition. It is soluble in dioxane, sparingly soluble in acetone, alcohol, chloroform, and methanol, and slightly soluble in ether. It is practically insoluble in water.



What does P-Care D40G look like?



What are the available doses of P-Care D40G?

Sorry No records found.

What should I talk to my health care provider before I take P-Care D40G?

Sorry No records found

How should I use P-Care D40G?

Gebauer's Pain Ease Medium Stream Spray and Mist Spray are vapocoolants (skin refrigerants) intended for topical application to skin, intact mucous membranes (oral cavity, nasal passage ways and the lips) and minor open wounds. Pain Ease instantly controls pain associated with injections (venipuncture, IV starts, cosmetic procedures), minor surgical procedures (such as lancing boils, incision and drainage of small abscesses and sutures) and the temporary relief of minor sports injuries (sprains, bruising, cuts and abrasions.

Wipe injection site vigorously and discard


What interacts with P-Care D40G?

Sorry No Records found


What are the warnings of P-Care D40G?

Sorry No Records found


What are the precautions of P-Care D40G?

Sorry No Records found


What are the side effects of P-Care D40G?

Sorry No records found


What should I look out for while using P-Care D40G?

Pain Ease is contraindicated in individuals with a history of hypersensitivity to 1,1,1,3,3-Pentafluoropropane and 1,1,1,2-Tetrafluoroethane. If skin irritation develops, discontinue use.

For external use only. Contents under pressure. For use on minor open wounds only. For use on intact oral mucous membranes only.


What might happen if I take too much P-Care D40G?

Treatment of acute overdosage is by supportive and symptomatic therapy. For chronic overdosage in the face of severe disease requiring continuous steroid therapy, the dosage of the corticosteroid may be reduced only temporarily, or alternate day treatment may be introduced.


How should I store and handle P-Care D40G?

Aerosol CanGebauer’s Pain Ease® Medium Stream Spray 3.5 fl. oz. (103.5mL) - P/N 0386-0008-031.0 fl. oz. (30mL) - P/N 0386-0008-04 Gebauer’s Pain Ease® Mist Spray 3.5 fl. oz. (103.5mL) - P/N 0386-0008-021.0 fl. oz. (30mL) - P/N 0386-0008-01For more information about this product contact Gebauer Company.Aerosol CanGebauer’s Pain Ease® Medium Stream Spray 3.5 fl. oz. (103.5mL) - P/N 0386-0008-031.0 fl. oz. (30mL) - P/N 0386-0008-04 Gebauer’s Pain Ease® Mist Spray 3.5 fl. oz. (103.5mL) - P/N 0386-0008-021.0 fl. oz. (30mL) - P/N 0386-0008-01For more information about this product contact Gebauer Company.Aerosol CanGebauer’s Pain Ease® Medium Stream Spray 3.5 fl. oz. (103.5mL) - P/N 0386-0008-031.0 fl. oz. (30mL) - P/N 0386-0008-04 Gebauer’s Pain Ease® Mist Spray 3.5 fl. oz. (103.5mL) - P/N 0386-0008-021.0 fl. oz. (30mL) - P/N 0386-0008-01For more information about this product contact Gebauer Company.Aerosol CanGebauer’s Pain Ease® Medium Stream Spray 3.5 fl. oz. (103.5mL) - P/N 0386-0008-031.0 fl. oz. (30mL) - P/N 0386-0008-04 Gebauer’s Pain Ease® Mist Spray 3.5 fl. oz. (103.5mL) - P/N 0386-0008-021.0 fl. oz. (30mL) - P/N 0386-0008-01For more information about this product contact Gebauer Company.


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids.

Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt retaining properties, are used in replacement therapy in adrenocortical deficiency states. Their synthetic analogs are used primarily for their anti-inflammatory effects in disorders of many organ systems.

Non-Clinical Toxicology
Pain Ease is contraindicated in individuals with a history of hypersensitivity to 1,1,1,3,3-Pentafluoropropane and 1,1,1,2-Tetrafluoroethane. If skin irritation develops, discontinue use.

For external use only. Contents under pressure. For use on minor open wounds only. For use on intact oral mucous membranes only.

Aminoglutethimide:

Amphotericin B injection and potassium-depleting agents:







Anticholinesterases:

Anticoagulants, oral

Antidiabetics:

Antitubercular drugs:

Cholestyramine: Cholestyramine may increase the clearance of oral corticosteroids.

Cyclosporine:

Digitalis glycosides:

Estrogens, including oral contraceptives:

Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin):

Hepatic Enzyme Inhibitors (e.g., ketoconazole, macrolide antibiotics such as erythromycin and troleandomycin):

Ketoconazole:

Nonsteroidal anti-inflammatory drugs (NSAIDs):

Skin tests:





1. Do not spray in the eyes.

2. Do not use this product on persons with poor circulation or insensitive skin.

3. When used to produce local freezing of tissues, adjacent skin areas may be protected by an application of petrolatum.

4. The freezing and thawing process may be painful, and freezing may lower local resistance to infection and delay healing.

5. Over application of the product might cause frostbite and/or after skin pigmentation.

6. Do not use on large areas of damaged skin, puncture wounds, animal bites or serious wounds.

7. Apply only to intact mucous membranes.

8. Do not use on genital mucous membranes.

Freezing can occasionally alter skin pigmentation.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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