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Perrigo Benzoyl Peroxide

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Overview

What is Perrigo Benzoyl Peroxide?

Benzoyl Peroxide Gel 5% and 10% (Hydroalcoholic Base Acne Gels) are topical preparations containing benzoyl peroxide as the active ingredient.

Benzoyl Peroxide Gel 5% contains: 5% benzoyl peroxide in a hydroalcoholic gel base formulated with alcohol (12%, denatured with tert-butyl alcohol and denatonium benzoate), citric acid, disodium lauryl sulfosuccinate, hypromellose, laureth-12, magnesium aluminum silicate, and purified water. Benzoyl Peroxide Gel 10% contains: 10% benzoyl peroxide in a hydroalcoholic gel base formulated with alcohol (20%, denatured with tert-butyl alcohol and denatonium benzoate), citric acid, hypromellose, laureth-12, magnesium aluminum silicate, and purified water.

The structural formula of benzoyl peroxide is:



What does Perrigo Benzoyl Peroxide look like?



What are the available doses of Perrigo Benzoyl Peroxide?

Sorry No records found.

What should I talk to my health care provider before I take Perrigo Benzoyl Peroxide?

Sorry No records found

How should I use Perrigo Benzoyl Peroxide?

Benzoyl Peroxide Gel 5% and 10% are indicated for use in the topical treatment of mild to moderate acne vulgaris. Benzoyl Peroxide Gel 5% and 10% may be used as an adjunct in acne treatment regimens including antibiotics, retinoic acid products, and sulfur/salicylic acid containing preparations.

It is recommended that therapy be initiated with Benzoyl Peroxide Gel 5%, applying the medication to the affected areas once a day during the first week, and twice a day thereafter as tolerated. Frequency of use should be adjusted to obtain the desired clinical response. Therapy with Benzoyl Peroxide Gel 10% may be initiated in patients who demonstrate accommodation to Benzoyl Peroxide Gel 5%.

Gentle cleansing of the affected areas prior to application of Benzoyl Peroxide Gel 5% or 10% may be beneficial.

Clinically visible improvements will normally occur by the third week of therapy. Maximum lesion reduction may be expected after approximately eight to twelve weeks of drug use. Continuing use of the drug is normally required to maintain a satisfactory clinical response.


What interacts with Perrigo Benzoyl Peroxide?

Benzoyl Peroxide Gel 5% and 10% should not be used in patients who have shown hypersensitivity to benzoyl peroxide or to any of the other ingredients in the products.



What are the warnings of Perrigo Benzoyl Peroxide?

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What are the precautions of Perrigo Benzoyl Peroxide?

General

For external use only. Avoid contact with eyes and mucous membranes.

Carcinogenesis, Mutagenesis, Impairment of Fertility

Based upon all available evidence, benzoyl peroxide is not considered to be a carcinogen. However, data from a study using mice known to be highly susceptible to cancer suggest that benzoyl peroxide acts as a tumor promoter. The clinical significance of the findings is not known.

Pregnancy

Animal reproduction studies have not been conducted with benzoyl peroxide. It is also not known whether benzoyl peroxide can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Benzoyl peroxide should be used by a pregnant woman only if clearly needed.

Nursing Mothers

It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when benzoyl peroxide is administered to a nursing woman.

Pediatric Use

Safety and effectiveness in children below the age of 12 have not been established.


What are the side effects of Perrigo Benzoyl Peroxide?

Contact sensitization reactions are associated with the use of topical benzoyl peroxide products and may be expected to occur in 10 to 25 of 1000 patients. The most frequent adverse reactions associated with benzoyl peroxide use are excessive erythema and peeling which may be expected to occur in 5 of 100 patients. Excessive erythema and peeling most frequently appear during the initial phase of drug use and may normally be controlled by reducing frequency of use.


What should I look out for while using Perrigo Benzoyl Peroxide?

Benzoyl Peroxide Gel 5% and 10% should not be used in patients who have shown hypersensitivity to benzoyl peroxide or to any of the other ingredients in the products.


What might happen if I take too much Perrigo Benzoyl Peroxide?

Sorry No Records found


How should I store and handle Perrigo Benzoyl Peroxide?

Store at 25°C (77°F); excursions permitted to 15°C-30°C (59°F-86°F).Benzoyl Peroxide Gel 5% (Hydroalcoholic Base Acne Gel) are supplied in 60 gram tubes.Benzoyl Peroxide Gel 5% NDC 21695-686-60Benzoyl Peroxide Gel 5% (Hydroalcoholic Base Acne Gel) are supplied in 60 gram tubes.Benzoyl Peroxide Gel 5% NDC 21695-686-60


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

The exact method of action of benzoyl peroxide in acne vulgaris is not known. Benzoyl peroxide is an antibacterial agent with demonstrated activity against This action, combined with the mild keratolytic effect of benzoyl peroxide is believed to be responsible for its usefulness in acne. Benzoyl peroxide is absorbed by the skin where it is metabolized to benzoic acid and excreted as benzoate in the urine.

Non-Clinical Toxicology
Benzoyl Peroxide Gel 5% and 10% should not be used in patients who have shown hypersensitivity to benzoyl peroxide or to any of the other ingredients in the products.

SKELAXIN may enhance the effects of alcohol, barbiturates and other CNS depressants.

For external use only. Avoid contact with eyes and mucous membranes.

Contact sensitization reactions are associated with the use of topical benzoyl peroxide products and may be expected to occur in 10 to 25 of 1000 patients. The most frequent adverse reactions associated with benzoyl peroxide use are excessive erythema and peeling which may be expected to occur in 5 of 100 patients. Excessive erythema and peeling most frequently appear during the initial phase of drug use and may normally be controlled by reducing frequency of use.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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