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Benzoyl Peroxide Wash

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Overview

What is PR Benzoyl Peroxide Wash?

DESCRIPTION:PR Benzoyl Peroxide Wash is intended for topical administration and contains Benzoyl Peroxide for use in the treatment of acne vulgaris. Benzoyl Peroxide is an oxidizing agent that possesses antibacterial properties and is classified s a keratolytic. Benzoyl Peroxide (C14H10O4) is represented by thefollowing chemical structure:O = C – O – O – C = O

Each mL of PR Benzoyl Peroxide Wash contains 70 mg of Benzoyl Peroxide in an emulsion based formulation consisting of: aloe, carbomer 940, cetyl alcohol, disodium oleamido MEA-sulfosuccinate, disodium EDTA, glyceryl stearate/PEG-100 stearate, glycerin, green tea, laureth-12, magnesium aluminum silicate, propylene glycol, purified water, sodium coco-sulfate, sodium lauroamphoacetate, xanthan gum.



What does PR Benzoyl Peroxide Wash look like?



What are the available doses of PR Benzoyl Peroxide Wash?

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What should I talk to my health care provider before I take PR Benzoyl Peroxide Wash?

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How should I use PR Benzoyl Peroxide Wash?

INDICATIONS AND USAGE:PR Benzoyl Peroxide Wash is indicated for the topical treatment of acne vulgaris.

DOSAGE AND ADMINISTRATION:PR Benzoyl Peroxide Wash: Apply to affected areas once or twice a day, or as directed by your physician. Wet skin and liberally apply to areas to be cleansed. Massage gently into skin for 10-20 seconds, working into a full lather. Rinse thoroughly and pat dry. If excessive drying occurs, control by rinsing of cleanser sooner or using less often.


What interacts with PR Benzoyl Peroxide Wash?

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What are the warnings of PR Benzoyl Peroxide Wash?

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What are the precautions of PR Benzoyl Peroxide Wash?

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What are the side effects of PR Benzoyl Peroxide Wash?

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What should I look out for while using PR Benzoyl Peroxide Wash?

CONTRAINDICATIONS:PR Benzoyl Peroxide Wash is contraindicated in persons with a known hypersensitivity to any of its ingredients.


What might happen if I take too much PR Benzoyl Peroxide Wash?

OVERDOSAGE:If excessive scaling, erythema or edema occurs, the use of this preparation should be discontinued. To hasten resolution of the adverse effects, cool compresses may be used. After symptoms and signs subside, a reduced dosage schedule may be cautiously tried if the reaction is judged to be due to excessive use and not allergenicity.


How should I store and handle PR Benzoyl Peroxide Wash?

Store at 25°C (77°F); excursions permitted to 15 to 30°C (59 to 86°F) [see USP Controlled Room Temperature]. Pharmacist: Dispense in a tight, light-resistant container with a child-resistant closure and medication guide. Store at 25°C (77°F); excursions permitted to 15 to 30°C (59 to 86°F) [see USP Controlled Room Temperature]. Pharmacist: Dispense in a tight, light-resistant container with a child-resistant closure and medication guide. HOW SUPPLIED:PR Benzoyl Peroxide Wash is supplied in a 16 oz bottle, NDC 42546-145-16.


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Clinical Information

Chemical Structure

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Clinical Pharmacology

CLINICAL PHARMACOLOGY:The mechanism of action of Benzoyl Peroxide is not totally understood but its antibacterial activity against Propionibacterium acnes is thought to be a major mode of action. In addition, patients treated with Benzoyl Peroxide show a reduction in lipids and free fatty acids, and mild desquamation (drying and peeling activity) with simultaneous reduction in comedones and acne lesions. Little is known about the percutaneous penetration, metabolism, and excretion of Benzoyl Peroxide, although it has been shown that Benzoyl Peroxide absorbed by the skin is metabolized to benzoic acid and then excreted as benzoate in the urine. There is no evidence of systemic toxicity caused by Benzoyl Peroxide in humans.

Non-Clinical Toxicology
CONTRAINDICATIONS:PR Benzoyl Peroxide Wash is contraindicated in persons with a known hypersensitivity to any of its ingredients.

Antacids containing magnesium trisilicate, when administered concomitantly with nitrofurantoin, reduce both the rate and extent of absorption.  The mechanism for this interaction probably is adsorption of nitrofurantoin onto the surface of magnesium trisilicate.

Uricosuric drugs, such as probenecid and sulfinpyrazone, can inhibit renal tubular secretion of nitrofurantoin.  The resulting increase in nitrofurantoin serum levels may increase toxicity, and the decreased urinary levels could lessen its efficacy as a urinary tract antibacterial.

WARNINGS:When using this product, avoid unnecessary sun exposure and use a sunscreen.PRECAUTIONS:General: For external use only. If severe irritation develops, discontinue use and institute appropriate therapy. After reaction clears, treatment may often be resumed with less frequent application. These preparations should not be used in or near the eyes or on mucous membranes.

ADVERSE REACTIONS:Allergic contact dermatitis and dryness have been reported with topical Benzoyl Peroxide therapy.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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