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Sodium Fluoride

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Overview

What is Pro-Den Rx?



What does Pro-Den Rx look like?



What are the available doses of Pro-Den Rx?

Sorry No records found.

What should I talk to my health care provider before I take Pro-Den Rx?

Sorry No records found

How should I use Pro-Den Rx?

For topical application to aid in the protection against dental caries. Neutral pH is especially safe for crowns and restorations.

Dispense ½ oz. (approx. 1 pump) of Pro-DenRx 2.0% Neutral Sodium Fluoride Solution into the provided mixing cup. Instruct patient to rinse vigorously for 30 seconds with ½ oz. of the solution around and between teeth, then expectorate. For maximum benefit repeat the rinse procedure with an additional ½ oz. of solution. Pro-DenRx 2.0% Neutral Sodium Fluoride Solution may also be applied full strength, with cotton pledgets, to teeth isolated with cotton rolls.


What interacts with Pro-Den Rx?

Sorry No Records found


What are the warnings of Pro-Den Rx?

Sorry No Records found


What are the precautions of Pro-Den Rx?

Sorry No Records found


What are the side effects of Pro-Den Rx?

Sorry No records found


What should I look out for while using Pro-Den Rx?

Hypersensitivity to fluoride.


What might happen if I take too much Pro-Den Rx?

Accidental ingestion of large amounts of fluoride can cause: nausea, vomiting, abdominal pain, diarrhea, stupor and/ or weakness (usually within 30 minutes). These symptoms may persist for 24 hours. If less than 5 mg fluoride/kg body weight (less than 23 mg fluoride/lb body weight) has been ingested, give calcium (milk) orally to relieve symptoms and observe for a few hours. If more than 5 mg fluoride/kg body weight (more than 23 mg fluoride/lb body weight) has been ingested, induce vomiting, give calcium (i.e., milk, 5% calcium gluconate or calcium lactate solution) and immediately seek medical assistance. For accidental ingestion of more than 15 mg fluoride/kg body weight (i.e., more than 6.9 mg fluoride/lb body weight) induce vomiting, transport and admit immediately to a hospital facility.


How should I store and handle Pro-Den Rx?

2.0% Neutral Sodium Fluoride (0.9% Fluoride Ion) oral solution supplied in a plastic bottle with child-resistant closure containing 64 fl. oz. (1.89 L). Store at room temperature. Protect from freezing. Do not store in direct sunlight.Rx OnlyRevised: 12/20171-800-433-6628Reorder Number: 2037MTDTManufactured forDen-Mat Holdings, LLC1017 W. Central Ave.Lompoc, CA 9343611©2017 Den-Mat Holdings, LLC. All rights reserved. 001395000 12/17AS2.0% Neutral Sodium Fluoride (0.9% Fluoride Ion) oral solution supplied in a plastic bottle with child-resistant closure containing 64 fl. oz. (1.89 L). Store at room temperature. Protect from freezing. Do not store in direct sunlight.Rx OnlyRevised: 12/20171-800-433-6628Reorder Number: 2037MTDTManufactured forDen-Mat Holdings, LLC1017 W. Central Ave.Lompoc, CA 9343611©2017 Den-Mat Holdings, LLC. All rights reserved. 001395000 12/17AS2.0% Neutral Sodium Fluoride (0.9% Fluoride Ion) oral solution supplied in a plastic bottle with child-resistant closure containing 64 fl. oz. (1.89 L). Store at room temperature. Protect from freezing. Do not store in direct sunlight.Rx OnlyRevised: 12/20171-800-433-6628Reorder Number: 2037MTDTManufactured forDen-Mat Holdings, LLC1017 W. Central Ave.Lompoc, CA 9343611©2017 Den-Mat Holdings, LLC. All rights reserved. 001395000 12/17AS2.0% Neutral Sodium Fluoride (0.9% Fluoride Ion) oral solution supplied in a plastic bottle with child-resistant closure containing 64 fl. oz. (1.89 L). Store at room temperature. Protect from freezing. Do not store in direct sunlight.Rx OnlyRevised: 12/20171-800-433-6628Reorder Number: 2037MTDTManufactured forDen-Mat Holdings, LLC1017 W. Central Ave.Lompoc, CA 9343611©2017 Den-Mat Holdings, LLC. All rights reserved. 001395000 12/17AS2.0% Neutral Sodium Fluoride (0.9% Fluoride Ion) oral solution supplied in a plastic bottle with child-resistant closure containing 64 fl. oz. (1.89 L). Store at room temperature. Protect from freezing. Do not store in direct sunlight.Rx OnlyRevised: 12/20171-800-433-6628Reorder Number: 2037MTDTManufactured forDen-Mat Holdings, LLC1017 W. Central Ave.Lompoc, CA 9343611©2017 Den-Mat Holdings, LLC. All rights reserved. 001395000 12/17AS2.0% Neutral Sodium Fluoride (0.9% Fluoride Ion) oral solution supplied in a plastic bottle with child-resistant closure containing 64 fl. oz. (1.89 L). Store at room temperature. Protect from freezing. Do not store in direct sunlight.Rx OnlyRevised: 12/20171-800-433-6628Reorder Number: 2037MTDTManufactured forDen-Mat Holdings, LLC1017 W. Central Ave.Lompoc, CA 9343611©2017 Den-Mat Holdings, LLC. All rights reserved. 001395000 12/17AS2.0% Neutral Sodium Fluoride (0.9% Fluoride Ion) oral solution supplied in a plastic bottle with child-resistant closure containing 64 fl. oz. (1.89 L). Store at room temperature. Protect from freezing. Do not store in direct sunlight.Rx OnlyRevised: 12/20171-800-433-6628Reorder Number: 2037MTDTManufactured forDen-Mat Holdings, LLC1017 W. Central Ave.Lompoc, CA 9343611©2017 Den-Mat Holdings, LLC. All rights reserved. 001395000 12/17AS2.0% Neutral Sodium Fluoride (0.9% Fluoride Ion) oral solution supplied in a plastic bottle with child-resistant closure containing 64 fl. oz. (1.89 L). Store at room temperature. Protect from freezing. Do not store in direct sunlight.Rx OnlyRevised: 12/20171-800-433-6628Reorder Number: 2037MTDTManufactured forDen-Mat Holdings, LLC1017 W. Central Ave.Lompoc, CA 9343611©2017 Den-Mat Holdings, LLC. All rights reserved. 001395000 12/17AS2.0% Neutral Sodium Fluoride (0.9% Fluoride Ion) oral solution supplied in a plastic bottle with child-resistant closure containing 64 fl. oz. (1.89 L). Store at room temperature. Protect from freezing. Do not store in direct sunlight.Rx OnlyRevised: 12/20171-800-433-6628Reorder Number: 2037MTDTManufactured forDen-Mat Holdings, LLC1017 W. Central Ave.Lompoc, CA 9343611©2017 Den-Mat Holdings, LLC. All rights reserved. 001395000 12/17AS2.0% Neutral Sodium Fluoride (0.9% Fluoride Ion) oral solution supplied in a plastic bottle with child-resistant closure containing 64 fl. oz. (1.89 L). Store at room temperature. Protect from freezing. Do not store in direct sunlight.Rx OnlyRevised: 12/20171-800-433-6628Reorder Number: 2037MTDTManufactured forDen-Mat Holdings, LLC1017 W. Central Ave.Lompoc, CA 9343611©2017 Den-Mat Holdings, LLC. All rights reserved. 001395000 12/17AS


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Non-Clinical Toxicology
Hypersensitivity to fluoride.

The concomitant use of benzodiazepines and opioids increases the risk of respiratory depression because of actions at different receptor sites in the CNS that control respiration. Benzodiazepines interact at GABAA sites and opioids interact primarily at mu receptors. When benzodiazepines and opioids are combined, the potential for benzodiazepines to significantly worsen opioid-related respiratory depression exists. Limit dosage and duration of concomitant use of benzodiazepines and opioids, and monitor patients closely for respiratory depression and sedation.

The benzodiazepines, including lorazepam, produce increased CNS-depressant effects when administered with other CNS depressants such as alcohol, barbiturates, antipsychotics, sedative/hypnotics, anxiolytics, antidepressants, narcotic analgesics, sedative antihistamines, anticonvulsants, and anesthetics.

Concomitant use of clozapine and lorazepam may produce marked sedation, excessive salivation, hypotension, ataxia, delirium, and respiratory arrest.

Concurrent administration of lorazepam with valproate results in increased plasma concentrations and reduced clearance of lorazepam. Lorazepam dosage should be reduced to approximately 50% when coadministered with valproate.

Concurrent administration of lorazepam with probenecid may result in a more rapid onset or prolonged effect of lorazepam due to increased half-life and decreased total clearance. Lorazepam dosage needs to be reduced by approximately 50% when coadministered with probenecid.

The effects of probenecid and valproate on lorazepam may be due to inhibition of glucuronidation.

Administration of theophylline or aminophylline may reduce the sedative effects of benzodiazepines, including lorazepam.

For Professional Office Use Only. This product is not intended for home or unsupervised consumer use. Do not swallow. Keep out of reach of children. Not recommended for children under the age of 6. Limited to topical use in the mouth only.

The following adverse reactions are possible in individuals hypersensitive to fluoride: eczema, atopic dermatitis, urticaria, gastric distress, headache, and weakness.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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