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QUADRAPAX

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Overview

What is QUADRAPAX?

Each 5 mL (one teaspoonful) for oral administration contains:

Phenobarbital, USP.......................................................16.2 mg

  ( May be habit forming)

Hyoscyamine sulfate, USP.........................................0.1037 mg

Atropine sulfate, USP.................................................0.0194 mg

Scopolamine hydrobromide, USP................................0.0065  mg

Alcohol...............................................................................23%



What does QUADRAPAX look like?



What are the available doses of QUADRAPAX?

Sorry No records found.

What should I talk to my health care provider before I take QUADRAPAX?

Sorry No records found

How should I use QUADRAPAX?

FDA has classified the following indications as "possibly" effective:  For use as adjunctive therapy in the treatment of irritable bowel syndrome (irritable colon, spastic colon, mucous colitis) and acute enterocolitis.  May also be useful as adjunctive therapy in the treatment of duodenal ulcer. 

IT HAS NOT BEEN SHOWN CONCLUSIVELY WHETHER ANTICHOLINERGIC/ANTISPASMODIC DRUGS AID IN THE HEALING OF A DUODENAL ULCER, DECREASE THE RATE OF RECURRENCES OR PREVENT COMPLICATIONS.

The dosage of

Quadrapax Elixir

should be adjusted to the needs of the individual patient to assure symptomatic control with a minimum of adverse effects.

Adults: 

One or two teaspoonfuls of elixir three to four times a day according to conditions and severity of symptoms.

Pediatric patients:

  may be dosed every 4 to 6 hours.

Starting dosage

Children under 2 years of age:

  as directed by a physician.


What interacts with QUADRAPAX?

Sorry No Records found


What are the warnings of QUADRAPAX?

Sorry No Records found


What are the precautions of QUADRAPAX?

Sorry No Records found


What are the side effects of QUADRAPAX?

Adverse reactions associated with anticholinergics and/or anticonvulsants are:  dry mouth; tachycardia; urinary hesitancy and retention; palpitation; blurred vision; prolonged pupil dilation; cycloplegia; increased ocular tension; loss of taste sense; headache; nervousness; drowsiness; weakness; dizziness; insomnia; nausea; vomiting; severe allergic reaction or drug idiosyncrasies, including anaphylaxis, hives and/or other dermal manifestations; decreased sweating; impotence; suppression of lactation; constipation; bloated feeling and musculoskeletal pain.  Elderly patients may react with symptoms of excitement, agitation and drowsiness to even small doses of the drug.  Phenobarbital may produce excitement in some patients, rather than a sedative effect.  In patients habituated to barbiturates, abrupt withdrawal may produce delirium or convulsions.


What should I look out for while using QUADRAPAX?

Quadrapax Elixir is contraindicated in patients with known hypersensitivity to any of the ingredients.  Phenobarbital is contraindicated in patients with acute intermittent porphyria and in those patients in which phenobarbital produces restlessness and/or excitement.

It is also contraindicated in patients with glaucoma, obstructive uropathy; paralytic ileus; myasthenia gravis; intestinal atony; unstable cardiovascular status in acute hemorrhage; hiatal hernia associated with reflux esophagitis; obstructive disease of the gastrointestinal tract; or severe ulcerative colitis.

Heat prostration can occur with belladonna alkaloids in high temperatures.

Diarrhea may be an early symptom of incomplete intestinal obstruction, especially in patients with ileostomy or colostomy.  In this instance, treatment with this drug could be harmful.

Quadrapax Elixir

may produce drowsiness and blurred vision.  The patient should be warned about engaging in hazardous work or activities requiring mental alertness, such as operating a motor vehicle or other machinery.  Phenobarbital may decrease the effect of anticoagulants, and larger doses of the anticoagulant may be needed for optimal effect.  When phenobarbital is discontinued, the dose of the anticoagulant may have to be decreased.  Phenobarbital may be habit forming and should not be administered to patients who are susceptible to addiction or to those with a history of physical and/or psychological drug dependence.

Barbiturates should be used with caution in patients with hepatic dysfunction.


What might happen if I take too much QUADRAPAX?

An overdose of

Quadrapax Elixir

is a potentially lethal overdose situation.  Call your doctor or a Poison Control Center immediately if an overdose is suspected.

SIGNS AND SYMPTOMS:

Characteristics of phenobarbital overdose include decreased consciousness leading to coma, bradycardia, bradypnea, hypothermia and hypotention.  Overdose may also lead to pulmonary edema and acute renal failure as result of shock.  Other symptoms of an overdose with this product include headache, nausea, vomiting, tachycardia, severe or persistent blurred vision, dilated pupils, hot and dry skin, dizziness or disorientation, severe dryness of the mouth, difficulty in swallowing, and CNS stimulation.

RECOMMENDED TREATMENT:

Treatment of overdose is supportive, and consists mainly in the maintenance of airway patency through endotracheal intubation and mechanical ventilation, correction of bradycardia and hypotention with intravenous fluids and vasopressors, if necessary, and removal of as much drug as possible from the body.  Depending on how much time has elapsed since ingestion of the drug, this may be accomplished through gastric lavage or use of activated charcoal.


How should I store and handle QUADRAPAX?

Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320Quadrapax Elixir is a purple colored, grape flavored liquid.1 Pint (16 fl oz.) bottles NDC 21695-970-16.Store at 20°- 25°C(68°- 77°F) [see USP Controlled Room Temperature].Excursions permitted to 15°- 30°C(59°- 86°F).Tamper evident by foil seal under cap.  Do not use if foil seal is broken or missing.WARNINGS:  KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.  IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY. Manufactured for:Acella PHARMACEUTICALS, LLCAcella Pharmaceuticals, LLCAlpharetta, GA  30009Iss. 03/11Relabeled by:Rebel Distributors CorpThousand Oaks, CA 91320