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QuilliChew ER

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Overview

What is QuilliChew ER?

QuilliChew ER (methylphenidate hydrochloride extended-release chewable tablets) is available in three dosage strengths - 20 mg, 30 mg and 40 mg. The dosage strengths are expressed in terms of methylphenidate hydrochloride equivalents; however only 15% of methylphenidate is present as methylphenidate hydrochloride salt. The remaining 85% is present as methylphenidate ionically-bound to the sulfonate groups of sodium polystyrene sulfonate particles. QuilliChew ER contains approximately 30% immediate-release and 70% extended-release methylphenidate.

The QuilliChew ER extended-release chewable tablets are cherry flavored.

Methylphenidate HCl is a central nervous system (CNS) stimulant. The chemical name is methyl α-phenyl-2-piperidineacetate hydrochloride, and its structural formula is shown in Figure 1.

Figure 1. Methylphenidate HCl Structure

Methylphenidate HCl is a white, odorless crystalline powder. Its solutions are acid to litmus. It is freely soluble in water and in methanol, soluble in alcohol, and slightly soluble in chloroform and in acetone.

QuilliChew ER also contains the following inactive ingredients: aspartame , cherry flavor, citric acid, crospovidone, D&C red #30 (for 30 mg strength), D&C red #7 (for 40 mg strength), guar gum, magnesium stearate, mannitol, microcrystalline cellulose, polyvinyl acetate, polyvinyl alcohol, povidone, silicon dioxide, sodium polystyrene sulfonate, talc, triacetin, xanthan gum.



What does QuilliChew ER look like?



What are the available doses of QuilliChew ER?

Extended-release chewable tablets:

20 mg equivalent of methylphenidate HCl available as a speckled, off-white, capsule-shaped coated tablet, debossed with "NP 12" on one side and functionally scored on the other side.

30 mg equivalent of methylphenidate HCl available as a speckled, light pink color, capsule-shaped coated tablet, debossed with "NP 13" on one side and functionally scored on the other side.

40 mg equivalent of methylphenidate HCl available as a speckled, dark pink to peach color, capsule-shaped coated tablet, debossed with "NP 14" on one side and plain (not scored) on the other side.

What should I talk to my health care provider before I take QuilliChew ER?

How should I use QuilliChew ER?

QuilliChew ER is indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) .

Prior to treating children, adolescents, and adults with CNS stimulants including QuilliChew ER, assess for the presence of cardiac disease (i.e., perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam)

Assess the risk of abuse prior to prescribing, and monitor for signs of abuse and dependence while on therapy. Maintain careful prescription records, educate patients about abuse, monitor for signs of abuse and overdose, and periodically re-evaluate the need for QuilliChew ER use


What interacts with QuilliChew ER?

Sorry No Records found


What are the warnings of QuilliChew ER?

Sorry No Records found


What are the precautions of QuilliChew ER?

Sorry No Records found


What are the side effects of QuilliChew ER?

Sorry No records found


What should I look out for while using QuilliChew ER?

Known hypersensitivity to methylphenidate or product components ()

Concurrent treatment with a monoamine oxidase inhibitor (MAOI), or use of an MAOI within the preceding 14 days (, )

CNS stimulants, including QuilliChew ER, other methylphenidate-containing products, and amphetamines, have a high potential for abuse and dependence. Assess the risk of abuse prior to prescribing, and monitor for signs of abuse and dependence while on therapy


What might happen if I take too much QuilliChew ER?

Consult with a Certified Poison Control Center (1-800-222-1222) for up-to-date guidance and advice on the management of overdosage with methylphenidate. Signs and symptoms of acute methylphenidate overdosage, resulting principally from overstimulation of the CNS and from excessive sympathomimetic effects, may include the following: nausea, vomiting, diarrhea, restlessness, anxiety, agitation, tremors, hyperreflexia, muscle twitching, convulsions (may be followed by coma), euphoria, confusion, hallucinations, delirium, sweating, flushing, headache, hyperpyrexia, tachycardia, palpitations, cardiac arrhythmias, hypertension, hypotension, tachypnea, mydriasis, dryness of mucous membranes, and rhabdomyolysis.


How should I store and handle QuilliChew ER?

Store at 20°C to 25ºC (68°F to 77ºF); excursions permitted from 15ºC to 30ºC (59ºF to 86ºF). [See USP Controlled Room Temperature.]LIDODERM (lidocaine patch 5%) is available as the following:Carton of 30 patches, packaged into individual child-resistant envelopes NDC 49999-419-30Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F). [See USP Controlled Room Temperature].For more information, call Endo Pharmaceuticals at 1-800-462-3636.Manufactured for: Malvern, PA 19355LIDODERM is a registered trademark of Hind Health Care, Inc.© 2015 Endo Pharmaceuticals Inc.  All rights reserved.114957 / January 2015LIDODERM (lidocaine patch 5%) is available as the following:Carton of 30 patches, packaged into individual child-resistant envelopes NDC 49999-419-30Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F). [See USP Controlled Room Temperature].For more information, call Endo Pharmaceuticals at 1-800-462-3636.Manufactured for: Malvern, PA 19355LIDODERM is a registered trademark of Hind Health Care, Inc.© 2015 Endo Pharmaceuticals Inc.  All rights reserved.114957 / January 2015LIDODERM (lidocaine patch 5%) is available as the following:Carton of 30 patches, packaged into individual child-resistant envelopes NDC 49999-419-30Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F). [See USP Controlled Room Temperature].For more information, call Endo Pharmaceuticals at 1-800-462-3636.Manufactured for: Malvern, PA 19355LIDODERM is a registered trademark of Hind Health Care, Inc.© 2015 Endo Pharmaceuticals Inc.  All rights reserved.114957 / January 2015LIDODERM (lidocaine patch 5%) is available as the following:Carton of 30 patches, packaged into individual child-resistant envelopes NDC 49999-419-30Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F). [See USP Controlled Room Temperature].For more information, call Endo Pharmaceuticals at 1-800-462-3636.Manufactured for: Malvern, PA 19355LIDODERM is a registered trademark of Hind Health Care, Inc.© 2015 Endo Pharmaceuticals Inc.  All rights reserved.114957 / January 2015LIDODERM (lidocaine patch 5%) is available as the following:Carton of 30 patches, packaged into individual child-resistant envelopes NDC 49999-419-30Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F). [See USP Controlled Room Temperature].For more information, call Endo Pharmaceuticals at 1-800-462-3636.Manufactured for: Malvern, PA 19355LIDODERM is a registered trademark of Hind Health Care, Inc.© 2015 Endo Pharmaceuticals Inc.  All rights reserved.114957 / January 2015LIDODERM (lidocaine patch 5%) is available as the following:Carton of 30 patches, packaged into individual child-resistant envelopes NDC 49999-419-30Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F). [See USP Controlled Room Temperature].For more information, call Endo Pharmaceuticals at 1-800-462-3636.Manufactured for: Malvern, PA 19355LIDODERM is a registered trademark of Hind Health Care, Inc.© 2015 Endo Pharmaceuticals Inc.  All rights reserved.114957 / January 2015LIDODERM (lidocaine patch 5%) is available as the following:Carton of 30 patches, packaged into individual child-resistant envelopes NDC 49999-419-30Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F). [See USP Controlled Room Temperature].For more information, call Endo Pharmaceuticals at 1-800-462-3636.Manufactured for: Malvern, PA 19355LIDODERM is a registered trademark of Hind Health Care, Inc.© 2015 Endo Pharmaceuticals Inc.  All rights reserved.114957 / January 2015LIDODERM (lidocaine patch 5%) is available as the following:Carton of 30 patches, packaged into individual child-resistant envelopes NDC 49999-419-30Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F). [See USP Controlled Room Temperature].For more information, call Endo Pharmaceuticals at 1-800-462-3636.Manufactured for: Malvern, PA 19355LIDODERM is a registered trademark of Hind Health Care, Inc.© 2015 Endo Pharmaceuticals Inc.  All rights reserved.114957 / January 2015


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Methylphenidate HCl is a central nervous system (CNS) stimulant.

Non-Clinical Toxicology
Known hypersensitivity to methylphenidate or product components ()

Concurrent treatment with a monoamine oxidase inhibitor (MAOI), or use of an MAOI within the preceding 14 days (, )

CNS stimulants, including QuilliChew ER, other methylphenidate-containing products, and amphetamines, have a high potential for abuse and dependence. Assess the risk of abuse prior to prescribing, and monitor for signs of abuse and dependence while on therapy









CNS stimulants, including QuilliChew ER, other methylphenidate-containing products, and amphetamines, have a high potential for abuse and dependenceAssess the risk of abuse prior to prescribing, and monitor for signs of abuse and dependence while on therapy

The following are discussed in more detail in other sections of the labeling:

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

Tips

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Interactions

Interactions

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