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Iodoquinol and Aloe Polysaccharide

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Overview

What is QUINJA?

Each gram of QUINJA contains 1.25% (12.5 mg) Iodoquinol and 1% (10 mg) Aloe Polysaccharides. Other ingredients: Purified Water, Carbomer 980, Magnesium Aluminum Silicate, PEG-20 Methyl Glucose Ether, Aminomethyl Propanol 95, Biopeptide, Propylene Glycol, Glycerine, SDA Alcohol 40 B, Benzyl Alcohol, Trolamine, FD&C Blue #1 and D&C Yellow #10.

Iodoquinol

Iodoquinol is an antifungal and antibacterial agent. Chemically, Iodoquinol is [5,7-diiodo-8-quinolinol] with the molecular formula (CHINO) and is represented by the following structural formula:

Aloe Polysaccharide

The Aloe Polysaccharide in QUINJA is a patented mixture of acetylated mannan aloe polysaccharide mixture with average molecular weights of 80 and 1300 kDa (CAS 89191- 46-8). Each purified acetylated mannan polysaccharide of specific molecular weight range and average is composed of the same repeating subunits shown below (where m is mannose, n is galactose and p is glucose monomers):



What does QUINJA look like?



What are the available doses of QUINJA?

Sorry No records found.

What should I talk to my health care provider before I take QUINJA?

Sorry No records found

How should I use QUINJA?

Based on a review of a related drug by the National Research Council and subsequent FDA classification for that drug, the indications are as follows: “Possibly” Effective: Contact or atopic dermatitis; impetiginized eczema; nummular eczema; endogenous chronic infectious dermatitis; stasis dermatitis; pyoderma; nuchal eczema and chronic eczematoid otitis externa; acne urticata; localized or disseminated neurodermatitis; lichen simplex chronicus; anogenital pruritus (vulvae, scroti, ani); folliculitis; bacterial dermatoses; mycotic dermatoses such as tinea (capitis, cruris, corporis, pedis); moniliasis; intertrigo. Final classification of the less-than- effective indications requires further investigation.

Apply to affected areas 3-4 times daily or as directed by a physician. Follow your physician’s directions regarding length of treatment after symptoms resolve.


What interacts with QUINJA?

Sorry No Records found


What are the warnings of QUINJA?

Sorry No Records found


What are the precautions of QUINJA?

Sorry No Records found


What are the side effects of QUINJA?

Sorry No records found


What should I look out for while using QUINJA?

QUINJA is contraindicated in those patients with a history of hypersensitivity to any components of the preparation.


What might happen if I take too much QUINJA?

Sorry No Records found


How should I store and handle QUINJA?

Store in a refrigerator 2° to 8°C (36° to 46°F).NDC # 69646-716-60……60 gram gel tubeNDC # 69646-716-01……1 gram gel individual pack NDC # 69646-716-10……10-count carton of 1 gram gel sample packs – not for resaleNDC # 69646-716-02…… 2 gram gel individual tube NDC # 69646-716-11…… 10-count carton of 2 gram gel sample tubes – not for resaleEach 1 gram gel pack contains multiple doses depending on the surface area treated.Each 2 gram gel tube contains multiple doses depending on the surface area treated.NDC # 69646-716-60……60 gram gel tubeNDC # 69646-716-01……1 gram gel individual pack NDC # 69646-716-10……10-count carton of 1 gram gel sample packs – not for resaleNDC # 69646-716-02…… 2 gram gel individual tube NDC # 69646-716-11…… 10-count carton of 2 gram gel sample tubes – not for resaleEach 1 gram gel pack contains multiple doses depending on the surface area treated.Each 2 gram gel tube contains multiple doses depending on the surface area treated.NDC # 69646-716-60……60 gram gel tubeNDC # 69646-716-01……1 gram gel individual pack NDC # 69646-716-10……10-count carton of 1 gram gel sample packs – not for resaleNDC # 69646-716-02…… 2 gram gel individual tube NDC # 69646-716-11…… 10-count carton of 2 gram gel sample tubes – not for resaleEach 1 gram gel pack contains multiple doses depending on the surface area treated.Each 2 gram gel tube contains multiple doses depending on the surface area treated.


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Non-Clinical Toxicology
QUINJA is contraindicated in those patients with a history of hypersensitivity to any components of the preparation.

A possible drug interaction of FOSCAVIR and intravenous pentamidine has been described. Concomitant treatment of four patients in the United Kingdom with FOSCAVIR and intravenous pentamidine may have caused hypocalcemia; one patient died with severe hypocalcemia. Toxicity associated with concomitant use of aerosolized pentamidine has not been reported.

Because of foscarnet's tendency to cause renal impairment, the use of FOSCAVIR should be avoided in combination with potentially nephrotoxic drugs such as aminoglycosides, amphotericin B, cyclosporine, acyclovir, methotrexate, tacrolimus and intravenous pentamidine (see above) unless the potential benefits outweigh the risks to the patient.

When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity.

Abnormal renal function has been observed in clinical practice during the use of FOSCAVIR and ritonavir, or FOSCAVIR, ritonavir, and saquinavir. (See )

Because of the risk of QT prolongation and the potential for torsades de pointes, the use of FOSCAVIR should be avoided in combination with agents known to prolong the QT interval including Class IA (e.g., quinidine or procainamide) or Class III (e.g., dofetilide, amiodarone, sotalol) antiarrhythmic agents, phenothiazines, tricyclic antidepressants, and certain macrolides and fluoroquinolones.

For external use only. Keep away from eyes. If irritation develops, the use of QUINJA should be discontinued and appropriate therapy instituted. Some discoloration of the skin, hair and fabrics may occur, but can be removed with normal cleansing and laundry. Not intended for use on infants or under diapers or occlusive dressings.

Iodoquinol may be absorbed through the skin and interfere with thyroid function tests. If such tests are contemplated, wait at least one month after discontinuance of therapy to perform these tests. The ferric chloride test for phenylketonuria (PKU) can yield a false positive result if Iodoquinol is present in the diaper or urine. Prolonged use may result in over- growth of non-susceptible organisms requiring appropriate therapy. Keep out of reach of children.

Adverse reactions from topical use of QUINJA is expected to be low when used as directed, due to low concentration of Iodoquinol present in this topical gel.

To achieve the equivalent of a common daily oral dose of nearly 2,000 mg Iodoquinol, one will need to use more than 2 full tubes of 60 g QUINJA in a single application. Adverse reactions from oral form of Iodoquinol (nearly 2,000 mg daily) have been reported: various forms of skin eruptions, hives, itching, nausea, vomiting, abdominal cramps, diarrhea, anusitis, fever, chills, headache, vertigo and enlargement of thyroid.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

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Interactions

Interactions

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