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Skin Lightener

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Overview

What is Skin Lightener?

DERMESSE SKIN LIGHTENER contains: Hydroquinone 40mg/gm.  See label on bottle for complete list of ingredients.  Following is its chemical structure:



What does Skin Lightener look like?



What are the available doses of Skin Lightener?

Sorry No records found.

What should I talk to my health care provider before I take Skin Lightener?

Sorry No records found

How should I use Skin Lightener?

DERMESSE SKIN LIGHTENER is indicated for the gradual bleaching of hyperpigmented skin conditions such as chlosma, melasma, freckles, senile lentigines and other unwanted areas of melanin hyperpigmentation.

A thin application of DERMESSE SKIN LIGHTENER should be applied to the affected area twice daily or as directed by a physician.  Consult product label for instructions on whether to rub in or not.  There is no recommendation for children under the age of 12 years of age except under the advice and supervision of a physician.


What interacts with Skin Lightener?

Prior history of sensitivity or allergic reaction to this product or any of its ingredients.  The safety of topical Hydroquinone use during pregnancy or in children (12 years and under) has not been established.



What are the warnings of Skin Lightener?

CAUTION:

  • Test for skin sensitivity before using Hydroquinone Cream by applying a small amount to an unbroken patch of skin and check within 24 hours. Minor redness is not a contraindication, but where there is itching and vesicle formation or excessive inflammatory response, further treatment is not advised. Close patient supervision is recommended. Contact with the eyes should be avoided. In case of accidental contact, patient should rinse eyes thoroughly with water and contact physician.  A bitter taste and anesthetic effect may occur if applied to lips.  Keep out of reach of children.  If no bleaching or lightening effect is noted after 2 months of treatment use, Hydroquinone Cream should be discontinued. This product is formulated for use as a skin bleaching agent and should not be used for the prevention of sunburn.
  • Sunscreen use is an essential aspect of Hydroquinone therapy because even minimal sunlight sustains melanocytic activity.  After clearing and during maintenance therapy, sun exposure should be avoided on bleached skin by application of a sunscreen or sunblock agent, or protective clothing to prevent repigmentation.  There are no sunblocking or sunscreening agents in DERMESSE SKIN LIGHTENER and since minimal sunlight exposure may reverse the bleaching effect of this preparation.  It should be used only at night or on areas of the body covered by protective clothing.  During the daytime, sunblocking or broad spectrum sunscreen preparations or protective clothing should be used to prevent the bleached areas from repigmentation.
  • Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
  • Warning: Contains sodium metabisulfite, a sulfite that may cause serious allergic type reactions (e.g., hives, itching, wheezing, anaphylaxis, severe asthma attack) in certain susceptible persons.


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What are the precautions of Skin Lightener?

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A. Pregnancy Category C

Animal reproduction studies have not been conducted with topical Hydroquinone. It is also not known whether Hydroquinone can cause fetal harm when used topically on a pregnant woman or can affect reproductive capacity.  It is not known to what degree, if any, topical Hydroquinone is absorbed systemically.  Topical Hydroquinone should be used in women only when clearly indicated.

B. Nursing mothers

It is not known whether topical Hydroquinone is absorbed or excreted in human milk. Caution is advised when topical Hydroquinone is used by a nursing mother.

C. Pediatric usage

Safety and effectiveness in children below the age of 12 years have not been established.


What are the side effects of Skin Lightener?

No systemic reactions have been reported. Occasional cutaneous hypersensitivity (localized contact dermatitis) may occur in which case the medication should be discontinued and the physician notified immediately


What should I look out for while using Skin Lightener?

Prior history of sensitivity or allergic reaction to this product or any of its ingredients.  The safety of topical Hydroquinone use during pregnancy or in children (12 years and under) has not been established.


What might happen if I take too much Skin Lightener?

There have been no systemic reactions reported from the use of topical Hydroquinone. However, treatment should be limited to relatively small areas of the body at one time since some patients experience a transient skin reddening and a mild burning sensation which does not preclude treatment.


How should I store and handle Skin Lightener?

Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature].DERMESSE SKIN LIGHTENER is available as follows:2 Oz. (57g) bottleDERMESSE SKIN LIGHTENER is available as follows:2 Oz. (57g) bottle


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Clinical Information

Chemical Structure

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Clinical Pharmacology

Topical application of hydroquinone produces a reversible depigmentation of the skin by inhibition of the enzymatic hydroquinone. oxidation of tyrosine to 3, 4-dihydroxyphenylalanine (dopa) and suppression of other melanocyte metabolic processes.

The selective inhibition of the enzyme affects melanogenesis in the melanocytes resulting in cessation of melanin formation and subsequent reduction in pigmentation.  Additional studies indicate Hydroquinone acts on the essential subcellular metabolic processes of melanocytes with resultant cytolysis, i.e. nonenzymediated depigmentation.

Exposure to sunlight or ultraviolet light will cause regimentation of the bleached areas, which may be prevented by the use of sunblocking agents.

Non-Clinical Toxicology
Prior history of sensitivity or allergic reaction to this product or any of its ingredients.  The safety of topical Hydroquinone use during pregnancy or in children (12 years and under) has not been established.

Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage.

Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin.

Absorption of tetracyclines is impaired by antacids containing aluminum, calcium, or magnesium, and iron-containing preparations.

The concurrent use of tetracycline and methoxyflurane has been reported to result in fatal renal toxicity.

Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective.

Administration of isotretinoin should be avoided shortly before, during, and shortly after minocycline therapy. Each drug alone has been associated with pseudotumor cerebri (see ).

Increased risk of ergotism when ergot alkaloids or their derivatives are given with tetracyclines.

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No systemic reactions have been reported. Occasional cutaneous hypersensitivity (localized contact dermatitis) may occur in which case the medication should be discontinued and the physician notified immediately

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

Tips

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Interactions

Interactions

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