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SulfaCleanse 8/4

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Overview

What is SulfaCleanse 8/4?

Sodium sulfacetamide is a sulfonamide with antibacterial activity while sulfur acts as a keratolytic agent. Chemically sodium sulfacetamide is N-[(4-aminophenyl) sulfonyl]-acetamide, monosodium salt, monohydrate. The structural formula is:

Each mL of contains 80 mg of sodium sulfacetamide and 40 mg of sulfur in a formulation consisting of: aloe barbadensis gel, butylated hydroxytoluene, cetyl alcohol, disodium oleamido MEA sulfosuccinate, edetate disodium, glyceryl stearate, green tea extract, magnesium aluminum silicate, methylparaben, PEG-100 stearate, petrolatum, propylparaben, purified water, sodium cocoyl isethionate, sodium methyl cocoyl taurate, sodium thiosulfate, stearyl alcohol, xanthan gum.



What does SulfaCleanse 8/4 look like?



What are the available doses of SulfaCleanse 8/4?

Sorry No records found.

What should I talk to my health care provider before I take SulfaCleanse 8/4?

Sorry No records found

How should I use SulfaCleanse 8/4?

SulfaCleanse 8/4 (sodium sulfacetamide 8% & sulfur 4%)

Apply once or twice daily to affected areas, or as directed by your physician. Wet skin and liberally apply to areas to be cleansed. Massage gently into skin for 10-20 seconds, working into a full lather, rinse thoroughly and pat dry. If drying occurs, it may be controlled by rinsing off sooner or using less often.


What interacts with SulfaCleanse 8/4?

SulfaCleanse 8/4 (sodium sulfacetamide 8% & sulfur 4%)


SulfaCleanse 8/4 (sodium sulfacetamide 8% & sulfur 4%)



What are the warnings of SulfaCleanse 8/4?



Although rare, sensitivity to sodium sulfacetamide may occur. Therefore, caution and careful supervision should be observed when prescribing this drug for patients who may be prone to hypersensitivity to topical sulfonamides. Systemic toxic reactions such as agranulocytosis, acute hemolytic anemia, purpura hemorrhagica, drug fever, jaundice, and contact dermatitis indicate hypersensitivity to sulfonamides. Particular caution should be employed if areas of denuded or abraded skin are involved.


What are the precautions of SulfaCleanse 8/4?

General

If irritation develops, use of the product should be discontinued and appropriate therapy instituted. Patients should be carefully observed for possible local irritation or sensitization during long-term therapy. The object of this therapy is to achieve desquamation without irritation, but sodium sulfacetamide and sulfur can cause reddening and scaling of the epidermis. These side effects are not unusual in the treatment of acne vulgaris, but patients should be cautioned about the possibility.

Information for Patients

Avoid contact with eyes, eyelids, lips and mucous membranes. If accidental contact occurs, rinse with water. If excessive irritation develops, discontinue use and consult your physician.

Carcinogenesis, Mutagenesis and Impairment of Fertility

Long-term studies in animals have not been performed to evaluate carcinogenic potential.

PREGNANCY

Animal reproduction studies have not been conducted with . It is also not known whether can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. should be given to a pregnant woman only if clearly needed.

NURSING MOTHERS

It is not known whether sodium sulfacetamide is excreted in the human milk following topical use of . However, small amounts of orally administered sulfonamides have been reported to be eliminated in human milk. In view of this and because many drugs are excreted in human milk, caution should be exercised when is administered to a nursing woman.

PEDIATRIC USE

Safety and effectiveness in children under the age of 12 has not been established.


What are the side effects of SulfaCleanse 8/4?

Although rare, sodium sulfacetamide may cause local irritation.


What should I look out for while using SulfaCleanse 8/4?

SulfaCleanse 8/4 (sodium sulfacetamide 8% & sulfur 4%)

SulfaCleanse 8/4 (sodium sulfacetamide 8% & sulfur 4%)

Although rare, sensitivity to sodium sulfacetamide may occur. Therefore, caution and careful supervision should be observed when prescribing this drug for patients who may be prone to hypersensitivity to topical sulfonamides. Systemic toxic reactions such as agranulocytosis, acute hemolytic anemia, purpura hemorrhagica, drug fever, jaundice, and contact dermatitis indicate hypersensitivity to sulfonamides. Particular caution should be employed if areas of denuded or abraded skin are involved.

FOR EXTERNAL USE ONLY

Keep out of reach of children.


What might happen if I take too much SulfaCleanse 8/4?

Sorry No Records found


How should I store and handle SulfaCleanse 8/4?

Store vials in a refrigerator at 2°C to 8°C (36°F to 46°F) until time of use.Keep vial in the outer carton in order to protect from light.DO NOT FREEZE. DO NOT SHAKE.Store vials in a refrigerator at 2°C to 8°C (36°F to 46°F) until time of use.Keep vial in the outer carton in order to protect from light.DO NOT FREEZE. DO NOT SHAKE.Store vials in a refrigerator at 2°C to 8°C (36°F to 46°F) until time of use.Keep vial in the outer carton in order to protect from light.DO NOT FREEZE. DO NOT SHAKE.SulfaCleanse 8/4 (sodium sulfacetamide 8% & sulfur 4%)


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

The most widely accepted mechanism of action of sulfonamides is the Woods-Fildes theory, which is based on the fact that sulfonamides act as competitive antagonists to paraaminobenzoic acid (PABA), an essential component for bacterial growth. While absorption through intact skin has not been determined, sodium sulfacetamide is readily absorbed from the gastrointestinal tract when taken orally and excreted in the urine, largely unchanged. The biological half-life has variously been reported as 7 to 12.8 hours. The exact mode of action of sulfur in the treatment of acne is unknown, but it has been reported that it inhibits the growth of Propionibacterium acnes and the formation of free fatty acids.

Non-Clinical Toxicology
SulfaCleanse 8/4 (sodium sulfacetamide 8% & sulfur 4%)

SulfaCleanse 8/4 (sodium sulfacetamide 8% & sulfur 4%)

Although rare, sensitivity to sodium sulfacetamide may occur. Therefore, caution and careful supervision should be observed when prescribing this drug for patients who may be prone to hypersensitivity to topical sulfonamides. Systemic toxic reactions such as agranulocytosis, acute hemolytic anemia, purpura hemorrhagica, drug fever, jaundice, and contact dermatitis indicate hypersensitivity to sulfonamides. Particular caution should be employed if areas of denuded or abraded skin are involved.

FOR EXTERNAL USE ONLY

Keep out of reach of children.

Potassium-sparing diuretics, angiotensin-converting enzyme inhibitors

If irritation develops, use of the product should be discontinued and appropriate therapy instituted. Patients should be carefully observed for possible local irritation or sensitization during long-term therapy. The object of this therapy is to achieve desquamation without irritation, but sodium sulfacetamide and sulfur can cause reddening and scaling of the epidermis. These side effects are not unusual in the treatment of acne vulgaris, but patients should be cautioned about the possibility.

Although rare, sodium sulfacetamide may cause local irritation.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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