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TALTZ
Overview
What is TALTZ?
Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) with neutralizing activity against IL-17A. Ixekizumab is produced by recombinant DNA technology in a recombinant mammalian cell line and purified using standard technology for bioprocessing. Ixekizumab is comprised of two identical light chain polypeptides of 219 amino acids each and two identical heavy chain polypeptides of 445 amino acids each, and has a molecular weight of 146,158 Daltons for the protein backbone of the molecule.
TALTZ injection is a sterile, preservative free, clear and colorless to slightly yellow solution, for subcutaneous use available as 80 mg of ixekizumab in a 1 mL single-dose prefilled autoinjector or a single-dose prefilled syringe. The prefilled autoinjector and prefilled syringe each contain a 1 mL glass syringe with a fixed 27 gauge ½ inch needle. The TALTZ 80 mg prefilled autoinjector and prefilled syringe are manufactured to deliver 80 mg of ixekizumab.
Each mL is composed of ixekizumab (80 mg); Citric Acid Anhydrous, USP (0.51 mg); Polysorbate 80, USP (0.3 mg); Sodium Chloride, USP (11.69 mg); Sodium Citrate Dihydrate, USP (5.11 mg); and Water for Injection, USP. The TALTZ solution has a pH of 5.3 – 6.1.
What does TALTZ look like?
What are the available doses of TALTZ?
Autoinjector
Prefilled Syringe
What should I talk to my health care provider before I take TALTZ?
How should I use TALTZ?
TALTZ is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
TALTZ is administered by subcutaneous injection. The recommended dose is 160 mg (two 80 mg injections) at Week 0, followed by 80 mg at Weeks 2, 4, 6, 8, 10, and 12, then 80 mg every 4 weeks.
What interacts with TALTZ?
Sorry No Records found
What are the warnings of TALTZ?
Sorry No Records found
What are the precautions of TALTZ?
Sorry No Records found
What are the side effects of TALTZ?
Sorry No records found
What should I look out for while using TALTZ?
TALTZ is contraindicated in patients with a previous serious hypersensitivity reaction, such as anaphylaxis, to ixekizumab or to any of the excipients .
What might happen if I take too much TALTZ?
In the event of overdosage, monitor the patient for any signs or symptoms of adverse reactions and institute appropriate symptomatic treatment immediately.
How should I store and handle TALTZ?
TALTZ is sterile and preservative-free. Discard any unused portion. 16. HOW SUPPLIED/STORAGE AND HANDLINGTopiramate Tablets 50 mg are yellow colored, round, biconvex, film coated tablets debossed with ‘1032’ on one side and ‘50’ on other side. Topiramate Tablets 50 mg are supplied as follows:NDC 60760-279-60 BOTTLES OF 6060760-279-90 BOTTLES OF 9016. HOW SUPPLIED/STORAGE AND HANDLINGTopiramate Tablets 50 mg are yellow colored, round, biconvex, film coated tablets debossed with ‘1032’ on one side and ‘50’ on other side. Topiramate Tablets 50 mg are supplied as follows:NDC 60760-279-60 BOTTLES OF 6060760-279-90 BOTTLES OF 9016. HOW SUPPLIED/STORAGE AND HANDLINGTopiramate Tablets 50 mg are yellow colored, round, biconvex, film coated tablets debossed with ‘1032’ on one side and ‘50’ on other side. Topiramate Tablets 50 mg are supplied as follows:NDC 60760-279-60 BOTTLES OF 6060760-279-90 BOTTLES OF 9016. HOW SUPPLIED/STORAGE AND HANDLINGTopiramate Tablets 50 mg are yellow colored, round, biconvex, film coated tablets debossed with ‘1032’ on one side and ‘50’ on other side. Topiramate Tablets 50 mg are supplied as follows:NDC 60760-279-60 BOTTLES OF 6060760-279-90 BOTTLES OF 90
