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ascorbic acid and cholecalciferol and sodium fluoride and vitamin A palmitate



What is Tri-Vit with Fluoride Drops?

Active ingredient for caries prophylaxis:

What does Tri-Vit with Fluoride Drops look like?

What are the available doses of Tri-Vit with Fluoride Drops?

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What should I talk to my health care provider before I take Tri-Vit with Fluoride Drops?

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How should I use Tri-Vit with Fluoride Drops?

Supplementation of the diet with vitamins A, D, and C. TRI-VIT with FLUORIDE 0.5 mg drops also provide fluoride for caries prophylaxis. TRI-VIT with FLUORIDE 0.5 mg (vitamins A, D, C and fluoride) drops provide fluoride in drop form for children ages 3 to 6 years in areas where the drinking water contains less than 0.3 ppm of fluoride and for children 6 years of age and older in areas where the drinking water contains 0.3 through 0.6 ppm of fluoride. Each 1 mL supplies sodium fluoride (0.5 mg fluoride) plus three basic vitamins. TRI-VIT with FLUORIDE 0.5 mg drops supply significant amounts of vitamins A, D, and C to supplement the diet, and to help assure that nutritional deficiencies of these vitamins will not develop. Thus, in a single easy-to-use preparation, infants and children obtain three essential vitamins plus fluoride. A comprehensive 5 1/2 year series of studies of the effectiveness of vitamin-fluoride products in caries protection has been published. Children in this continuing study lived in an area where the water supply contained only 0.05 ppm fluoride. The subjects were divided into two groups, one which used only non-fluoridated vitamin products and other vitamin-fluoride products. The three-year interim report showed 63% fewer carious surfaces in primary teeth and 43% fewer carious surfaces in permanent teeth of the children taking vitamin-fluoride products. After four years the studies continued to support the effectiveness of vitamin-fluoride products, showing a reduction in carious surfaces of 68% in primary teeth and 46% in permanent teeth. Results at the end of 5 1/2 years further confirmed the previous findings and indicated that significant reductions in dental caries are apparent with the continued use of vitamin-fluoride products. 

1 mL daily, or as prescribed. May be dropped directly into mouth with dropper, or mixed with fruit juice, cereal or other food.

What interacts with Tri-Vit with Fluoride Drops?

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What are the warnings of Tri-Vit with Fluoride Drops?

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What are the precautions of Tri-Vit with Fluoride Drops?

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What are the side effects of Tri-Vit with Fluoride Drops?

Allergic rash and other idiosyncrasies have been rarely reported. 

What should I look out for while using Tri-Vit with Fluoride Drops?

As with all medicines, keep out of the reach of children. 

What might happen if I take too much Tri-Vit with Fluoride Drops?

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How should I store and handle Tri-Vit with Fluoride Drops?

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Clinical Information

Chemical Structure

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Clinical Pharmacology

It is well established that fluoridation of the water supply (1 ppm fluoride) during the period of tooth development leads to a significant decrease in the incidence of dental caries. Hydroxyapatite is the principal crystal for all calcified tissue in the human body. The fluoride ion reacts with the in the tooth as it is formed to produce the more caries-resistant crystal, . Three stages of fluoride deposition in tooth enamel can be distinguished: 1) Small amounts (reflecting the low levels of fluoride in tissue fluids) are incorporated into the enamel crystals while they are being formed. 2) After enamel has been laid down, fluoride deposition continues in the surface enamel. Diffusion of fluoride from the surface inward is apparently restricted. 3) After eruption, the surface enamel acquires fluoride from water, food, supplementary fluoride, and smaller amounts from saliva.

Non-Clinical Toxicology
As with all medicines, keep out of the reach of children. 

Bile acid sequestering agents such as cholestyramine and colestipol may interfere with the action of ursodiol by reducing its absorption. Aluminum-based antacids have been shown to adsorb bile acids and may be expected to interfere with ursodiol in the same manner as the bile acid sequestering agents. Estrogens, oral contraceptives, and clofibrate (and perhaps other lipid-lowering drugs) increase hepatic cholesterol secretion, and encourage cholesterol gallstone formation and hence may counteract the effectiveness of ursodiol.

The suggested dose should not be exceeded since dental fluorosis may result from continued ingestion of large amounts of fluoride. When prescribing TRI-VIT with FLUORIDE 0.5 mg drops:1) Determine the fluoride content of the drinking water from all major sources.2)  Make sure the child is not receiving significant amounts of fluoride from other sources such as medications and swallowed toothpaste. 3)  Periodically check to make sure that the child does not develop significant dental fluorosis. TRI-VIT with FLUORIDE 0.5 mg drops should be dispensed in the original plastic container, since contact with glass leads to instability and precipitation. (The amount of sodium fluoride in a 50-mL size is well below the maximum to be dispensed at one time according to recommendations of the American Dental Association.)

Allergic rash and other idiosyncrasies have been rarely reported. 



This information is obtained from the National Institute of Health's Standard Packaging Label drug database.

While we update our database periodically, we cannot guarantee it is always updated to the latest version.



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