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Trisodium Citrate dihydrate
Overview
What is triCitrasol?
triCitrasol
Each 30 mL of
contains:
pH adjusted with Citric Acid
pH: 6.3 – 6.6
What does triCitrasol look like?
What are the available doses of triCitrasol?
Sorry No records found.
What should I talk to my health care provider before I take triCitrasol?
Sorry No records found
How should I use triCitrasol?
triCitrasol
triCitrasol
triCitrasol
The
/HES solution is stable for up to 24 hours at room temperature after mixing.
Refer to the manufacturer's Operator's Manual of the apheresis medical device for the directions to perform the granulocytapheresis procedure.
The apheresis system will control the amount of the citrate/6% solution of HES that is added to the whole blood and the method of administration of the solution. Refer to the Operator's Manual of the apheresis medical device.
What interacts with triCitrasol?
NOT FOR DIRECT INTRAVENOUS INFUSION.
What are the warnings of triCitrasol?
Array
What are the precautions of triCitrasol?
General
Aseptic technique must be maintained at all times.
triCitrasol
The cap/stopper system provides a biological barrier and should be intact – discard product if system is comprised.
Information for Patients
None.
Laboratory Tests
There are no laboratory tests for the drug product at this time.
Drug Interactions
There are no adverse reactions for the addition of the product to the rouleaux agent.
Carcinogenesis, mutagenesis, impairment of fertility
Long-term studies in animals have not been performed to evaluate the carcinogenic potential of
.
Pregnancy
Long-term studies in animals have not been performed to evaluate the effects of
on pregnant women.
Pediatric Use
The safety and effectiveness of
in children have not been established.
What are the side effects of triCitrasol?
Citrate reactions or toxicity may occur with the infusion of blood products containing citrate anticoagulant
. The recipient of the citrated blood product should be monitored for the signs and symptoms of citrate toxicity
. The signs and symptoms of citrate toxicity begin with paresthesia, a "tingling" sensation around the mouth or in the extremities, followed by severe reactions that are characterized by chills, stomach cramps, or pressure in the chest, followed by more severe reactions that are characterized by hypotension and possible cardiac arrhythmia
. Citrate toxicity may occur more frequently in patients that are hypothermic
, have impaired liver or renal function
, or have low calcium levels because of an underlying disease
.
What should I look out for while using triCitrasol?
NOT FOR DIRECT INTRAVENOUS INFUSION.
CONCENTRATED ANTICOAGULANT – DILUTE PRIOR TO USE.
What might happen if I take too much triCitrasol?
Since the bottle of
contains only 30mL of the product, it is impossible to overdose the addition of the product to the 6% solution of HES. However, in the event of a reaction to the infusion of citrated blood products, evaluate the patient and institute appropriate corrective actions
.
How should I store and handle triCitrasol?
triCitrasol®triCitrasol®
Clinical Information
Chemical Structure
No Image foundClinical Pharmacology
A sodium citrate solution acts as an anticoagulant by the action of the citrate ion chelating free ionized calcium; thus, the calcium ion is unavailable to the coagulation system
.
Non-Clinical Toxicology
NOT FOR DIRECT INTRAVENOUS INFUSION.CONCENTRATED ANTICOAGULANT – DILUTE PRIOR TO USE.
There are no adverse reactions for the addition of the product to the rouleaux agent.
Aseptic technique must be maintained at all times.
triCitrasol
The cap/stopper system provides a biological barrier and should be intact – discard product if system is comprised.
Citrate reactions or toxicity may occur with the infusion of blood products containing citrate anticoagulant . The recipient of the citrated blood product should be monitored for the signs and symptoms of citrate toxicity . The signs and symptoms of citrate toxicity begin with paresthesia, a "tingling" sensation around the mouth or in the extremities, followed by severe reactions that are characterized by chills, stomach cramps, or pressure in the chest, followed by more severe reactions that are characterized by hypotension and possible cardiac arrhythmia . Citrate toxicity may occur more frequently in patients that are hypothermic , have impaired liver or renal function , or have low calcium levels because of an underlying disease .
Reference
This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"
While we update our database periodically, we cannot guarantee it is always updated to the latest version.
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