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Ultravist

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Overview

What is Ultravist?

ULTRAVIST (iopromide) Injection is a nonionic, water soluble x-ray contrast agent for intravascular administration. The chemical name for iopromide is -Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]--methyl- 1,3- benzenedicarboxamide. Iopromide has a molecular weight of 791.12 (iodine content 48.12%).

Iopromide has the following structural formula:

ULTRAVIST Injection is a nonionic sterile, clear, colorless to slightly yellow, odorless, pyrogen-free aqueous solution of iopromide, containing 2.42 mg/mL tromethamine buffer and 0.1 mg/mL edetate calcium disodium stabilizer.

ULTRAVIST Injection is available in three strengths:

240 mg Iodine per mL provides 498.72 mg/mL iopromide

300 mg Iodine per mL provides 623.4 mg/mL iopromide

370 mg Iodine per mL provides 768.86 mg/mL iopromide

During the manufacture of ULTRAVIST Injection, sodium hydroxide or hydrochloric acid may be added for pH adjustment. ULTRAVIST Injection has a pH of 7.4 (6.5–8) at 25± 2°C, is sterilized by autoclaving and contains no preservatives.

The iodine concentrations (mg Iodine per mL) available have the following physicochemical properties:

Solutions of ULTRAVIST Injection 240 mg Iodine per mL, 300 mg Iodine per mL and 370 mg Iodine per mL have osmolalities from approximately 1.7 to 2.7 times that of plasma (285 mOsmol/kg water).



What does Ultravist look like?



What are the available doses of Ultravist?

ULTRAVIST Injection is available in three strengths: 240 mg Iodine per mL; 300 mg Iodine per mL; 370 mg Iodine per mL. ()

What should I talk to my health care provider before I take Ultravist?

How should I use Ultravist?

ULTRAVIST Injection is an iodinated contrast agent indicated for:

The volume and rate of injection of the contrast agent will vary depending on the injection site and the area being examined. Inject contrast at rates approximately equal to the flow rate in the vessel being injected.


What interacts with Ultravist?

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What are the warnings of Ultravist?

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What are the precautions of Ultravist?

Sorry No Records found


What are the side effects of Ultravist?

Sorry No records found


What should I look out for while using Ultravist?

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What might happen if I take too much Ultravist?

The adverse effects of overdosage are life-threatening and affect mainly the pulmonary and cardiovascular systems. Treatment of an overdosage is directed toward the support of all vital functions, and prompt institution of symptomatic therapy.

ULTRAVIST Injection binds negligibly to plasma or serum protein and can, therefore, be dialyzed.


How should I store and handle Ultravist?

Store tenofovir disoproxil fumarate tablets at 25 °C (77 °F), excursions permitted to 15°C to 30°C (59°F to 86°F) (see USP Controlled Room Temperature).Keep the bottle tightly closed. Do not use if seal over bottle opening is broken or missing.Store tenofovir disoproxil fumarate tablets at 25 °C (77 °F), excursions permitted to 15°C to 30°C (59°F to 86°F) (see USP Controlled Room Temperature).Keep the bottle tightly closed. Do not use if seal over bottle opening is broken or missing.ULTRAVIST Injection is a sterile, clear, colorless to slightly yellow, odorless, pyrogen-free aqueous solution available in four strengths.ULTRAVIST Injection 240 mg Iodine per mLULTRAVIST Injection 300 mg Iodine per mLULTRAVIST Injection 370 mg Iodine per mLStore ULTRAVIST at 25°C (77°F); excursions permitted to 15–30°C (59–86°F) and protected from light.ULTRAVIST Injection is a sterile, clear, colorless to slightly yellow, odorless, pyrogen-free aqueous solution available in four strengths.ULTRAVIST Injection 240 mg Iodine per mLULTRAVIST Injection 300 mg Iodine per mLULTRAVIST Injection 370 mg Iodine per mLStore ULTRAVIST at 25°C (77°F); excursions permitted to 15–30°C (59–86°F) and protected from light.ULTRAVIST Injection is a sterile, clear, colorless to slightly yellow, odorless, pyrogen-free aqueous solution available in four strengths.ULTRAVIST Injection 240 mg Iodine per mLULTRAVIST Injection 300 mg Iodine per mLULTRAVIST Injection 370 mg Iodine per mLStore ULTRAVIST at 25°C (77°F); excursions permitted to 15–30°C (59–86°F) and protected from light.ULTRAVIST Injection is a sterile, clear, colorless to slightly yellow, odorless, pyrogen-free aqueous solution available in four strengths.ULTRAVIST Injection 240 mg Iodine per mLULTRAVIST Injection 300 mg Iodine per mLULTRAVIST Injection 370 mg Iodine per mLStore ULTRAVIST at 25°C (77°F); excursions permitted to 15–30°C (59–86°F) and protected from light.ULTRAVIST Injection is a sterile, clear, colorless to slightly yellow, odorless, pyrogen-free aqueous solution available in four strengths.ULTRAVIST Injection 240 mg Iodine per mLULTRAVIST Injection 300 mg Iodine per mLULTRAVIST Injection 370 mg Iodine per mLStore ULTRAVIST at 25°C (77°F); excursions permitted to 15–30°C (59–86°F) and protected from light.


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Clinical Information

Chemical Structure

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Clinical Pharmacology

Iopromide is a nonionic, water soluble, tri-iodinated x-ray contrast agent for intravascular administration.

Intravascular injection of iopromide opacifies those vessels in the path of flow of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs.

Non-Clinical Toxicology
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See Table 2 for clinically significant drug interactions with diclofenac.

Life-threatening or fatal, anaphylactoid reactions, may occur during or after ULTRAVIST administration. Manifestations include respiratory arrest, laryngospasm, bronchospasm, angioedema, and shock. Increased risk is associated with a history of previous reaction to a contrast agent (3-fold), a known sensitivity to iodine and known allergic disorders (that is, bronchial asthma, hay fever and food allergies) or other hypersensitivities (2-fold) Exercise extreme caution when considering the use of iodinated contrast agents in patients with these histories or disorders.

Emergency facilities and personnel trained in the treatment of anaphylactoid reactions should be available for at least 30 to 60 minutes after ULTRAVIST administration.

The most important adverse drug reactions in patients receiving ULTRAVIST are anaphylactoid shock, contrast induced acute kidney injury, coma, cerebral infarction, stroke, brain edema, convulsion, arrhythmia, cardiac arrest, myocardial ischemia, myocardial infarction, cardiac failure, bradycardia, cyanosis, hypotension, shock, dyspnea, pulmonary edema, respiratory insufficiency and aspiration.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

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Interactions

Interactions

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