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vancomycin hydrochloride

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Overview

What is vancomycin hydrochloride?

Vancomycin Hydrochloride Capsules USP for oral administration contain chromatographically purified vancomycin hydrochloride, a tricyclic glycopeptide antibiotic derived from (formerly ), which has the chemical formula CHClNO•HCl. The molecular weight of vancomycin hydrochloride is 1485.73; 500 mg of the base is equivalent to 0.34 mmol.

The capsules contain vancomycin hydrochloride USP equivalent to 125 mg (0.08 mmol) or 250 mg (0.17 mmol) vancomycin. The capsules also contain FD&C Blue No. 2, gelatin, iron oxide, polyethylene glycol, titanium dioxide, and other inactive ingredients.

Vancomycin hydrochloride has the structural formula:



What does vancomycin hydrochloride look like?



What are the available doses of vancomycin hydrochloride?

Vancomycin Hydrochloride Capsules USP, 125 mg* have an opaque blue cap and opaque brown body imprinted with “3125” on the cap and “VANCOCIN HCL 125 MG” on the body in white ink.

Vancomycin Hydrochloride Capsules USP, 250 mg* have an opaque blue cap and opaque lavender body imprinted with “3126” on the cap and “VANCOCIN HCL 250 MG” on the body in white ink.

*Equivalent to vancomycin.

What should I talk to my health care provider before I take vancomycin hydrochloride?

How should I use vancomycin hydrochloride?

Vancomycin Hydrochloride Capsules are indicated for the treatment of e-associated diarrhea. Vancomycin Hydrochloride Capsules are also used for the treatment of enterocolitis caused by (including methicillin-resistant strains). Parenteral administration of vancomycin is not effective for the above infections; therefore, Vancomycin Hydrochloride Capsules must be given orally for these infections.

Orally administered Vancomycin Hydrochloride Capsules are not effective for other types of infections.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Vancomycin Hydrochloride Capsules and other antibacterial drugs, Vancomycin Hydrochloride Capsules should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Vancomycin Hydrochloride Capsules are used in treating -associated diarrhea and staphylococcal enterocolitis.


What interacts with vancomycin hydrochloride?

Sorry No Records found


What are the warnings of vancomycin hydrochloride?

Sorry No Records found


What are the precautions of vancomycin hydrochloride?

Sorry No Records found


What are the side effects of vancomycin hydrochloride?

Sorry No records found


What should I look out for while using vancomycin hydrochloride?

Vancomycin Hydrochloride Capsules are contraindicated in patients with known hypersensitivity to vancomycin.


What might happen if I take too much vancomycin hydrochloride?

Supportive care is advised, with maintenance of glomerular filtration. Vancomycin is poorly removed by dialysis. Hemofiltration and hemoperfusion with polysulfone resin have been reported to result in increased vancomycin clearance.

To obtain up-to-date information about the treatment of overdose, a good resource is your certified Regional Poison Control Center. Telephone numbers of certified poison control centers are listed in the . In managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics.


How should I store and handle vancomycin hydrochloride?

Store VPRIV at 2 °C to 8°C (36°F to 46°F). Do not use VPRIV after the expiration date on the vial. Do not freeze.Protect vial from light.Store VPRIV at 2 °C to 8°C (36°F to 46°F). Do not use VPRIV after the expiration date on the vial. Do not freeze.Protect vial from light.Vancomycin Hydrochloride Capsules USP are available in two strengths as follows: The 125 mg* capsules have an opaque blue cap and opaque brown body imprinted with “3125” on the cap and “VANCOCIN HCL 125 MG” on the body in white ink.NDC 62559-390-20: Carton containing 2 blister packs. Each blister pack contains 10 capsules for a total of 20 capsules per carton.NDC 62559-390-50: Bottle of 50 capsules.The 250 mg* capsules have an opaque blue cap and opaque lavender body imprinted with “3126” on the cap and “VANCOCIN HCL 250 MG” on the body in white ink. NDC 62559-391-20: Carton containing 2 blister packs. Each blister pack contains 10 capsules for a total of 20 capsules per carton.NDC 62559-391-50: Bottle of 50 capsules.Store at controlled room temperature, 59° to 86°F (15° to 30°C). *Equivalent to vancomycin. Vancomycin Hydrochloride Capsules USP are available in two strengths as follows: The 125 mg* capsules have an opaque blue cap and opaque brown body imprinted with “3125” on the cap and “VANCOCIN HCL 125 MG” on the body in white ink.NDC 62559-390-20: Carton containing 2 blister packs. Each blister pack contains 10 capsules for a total of 20 capsules per carton.NDC 62559-390-50: Bottle of 50 capsules.The 250 mg* capsules have an opaque blue cap and opaque lavender body imprinted with “3126” on the cap and “VANCOCIN HCL 250 MG” on the body in white ink. NDC 62559-391-20: Carton containing 2 blister packs. Each blister pack contains 10 capsules for a total of 20 capsules per carton.NDC 62559-391-50: Bottle of 50 capsules.Store at controlled room temperature, 59° to 86°F (15° to 30°C). *Equivalent to vancomycin. Vancomycin Hydrochloride Capsules USP are available in two strengths as follows: The 125 mg* capsules have an opaque blue cap and opaque brown body imprinted with “3125” on the cap and “VANCOCIN HCL 125 MG” on the body in white ink.NDC 62559-390-20: Carton containing 2 blister packs. Each blister pack contains 10 capsules for a total of 20 capsules per carton.NDC 62559-390-50: Bottle of 50 capsules.The 250 mg* capsules have an opaque blue cap and opaque lavender body imprinted with “3126” on the cap and “VANCOCIN HCL 250 MG” on the body in white ink. NDC 62559-391-20: Carton containing 2 blister packs. Each blister pack contains 10 capsules for a total of 20 capsules per carton.NDC 62559-391-50: Bottle of 50 capsules.Store at controlled room temperature, 59° to 86°F (15° to 30°C). *Equivalent to vancomycin. Vancomycin Hydrochloride Capsules USP are available in two strengths as follows: The 125 mg* capsules have an opaque blue cap and opaque brown body imprinted with “3125” on the cap and “VANCOCIN HCL 125 MG” on the body in white ink.NDC 62559-390-20: Carton containing 2 blister packs. Each blister pack contains 10 capsules for a total of 20 capsules per carton.NDC 62559-390-50: Bottle of 50 capsules.The 250 mg* capsules have an opaque blue cap and opaque lavender body imprinted with “3126” on the cap and “VANCOCIN HCL 250 MG” on the body in white ink. NDC 62559-391-20: Carton containing 2 blister packs. Each blister pack contains 10 capsules for a total of 20 capsules per carton.NDC 62559-391-50: Bottle of 50 capsules.Store at controlled room temperature, 59° to 86°F (15° to 30°C). *Equivalent to vancomycin. Vancomycin Hydrochloride Capsules USP are available in two strengths as follows: The 125 mg* capsules have an opaque blue cap and opaque brown body imprinted with “3125” on the cap and “VANCOCIN HCL 125 MG” on the body in white ink.NDC 62559-390-20: Carton containing 2 blister packs. Each blister pack contains 10 capsules for a total of 20 capsules per carton.NDC 62559-390-50: Bottle of 50 capsules.The 250 mg* capsules have an opaque blue cap and opaque lavender body imprinted with “3126” on the cap and “VANCOCIN HCL 250 MG” on the body in white ink. NDC 62559-391-20: Carton containing 2 blister packs. Each blister pack contains 10 capsules for a total of 20 capsules per carton.NDC 62559-391-50: Bottle of 50 capsules.Store at controlled room temperature, 59° to 86°F (15° to 30°C). *Equivalent to vancomycin.


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Vancomycin is an antibacterial drug (see[]).

Non-Clinical Toxicology
Vancomycin Hydrochloride Capsules are contraindicated in patients with known hypersensitivity to vancomycin.

Drug Interactions:

Prilocaine may contribute to the formation of methemoglobin in patients treated with other drugs known to cause this condition

Specific interaction studies with lidocaine/prilocaine and class III anti-arrhythmic drugs (e.g., amiodarone, bretylium, sotalol, doetilide) have not been performed, but caution is advised (see WARNINGS).

Should lidocaine and prilocaine cream be used concomitantly with other products containing lidocaine and/or prilocaine, cumulative doses from all formulations must be considered.

This preparation for the treatment of colitis is for oral use only and is not systemically absorbed. Vancomycin Hydrochloride Capsules must be given orally for treatment of staphylococcal enterocolitis and associated diarrhea. Orally administered Vancomycin Hydrochloride Capsules are not effective for other types of infections.

Parenteral administration of vancomycin is effective for treatment of staphylococcal enterocolitis and -associated diarrhea. If parenteral vancomycin therapy is desired, use an intravenous preparation of vancomycin and consult the package insert accompanying that preparation

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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