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HYDROCORTISONE ACETATE, IODOQUINOL

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Overview

What is Vytone?

Each gram contains 19 mg of hydrocortisone acetate and 10 mg iodoquinol in a vehicle consisting of: aloe vera powder, amino methylpropanol 95%, benzyl alcohol, carbomer, citric acid anhydrous, D&C yellow #10, FD&C blue #1, glycerin, glyceryl polymethacrylate, magnesium aluminum silicate, palmitoyl oligopeptide, PPG-20 methyl glucose ether, propylene glycol, purified water and SD Alcohol 40B.

Hydrocortisone acetate is an anti-inflammatory and antipruritic agent. Chemically, hydrocortisone acetate is [Pregn-4-ene-3, 20-dione, 21-(acetyloxy)-11, 17-dihydroxy-, (11-ß)-] with the molecular formula (C H O ) and is represented by the following structural formula:

Iodoquinol is an antifungal and antibacterial agent. Chemically, Iodoquinol is [5,7-diiodo-8-quinolinol] with the molecular formula (C H I NO) and is represented by the following structural formula:



What does Vytone look like?



What are the available doses of Vytone?

Sorry No records found.

What should I talk to my health care provider before I take Vytone?

Sorry No records found

How should I use Vytone?

Based on a review of a related drug by the National Research Council and subsequent FDA classification for that drug, the indications are as follows: “Possibly” Effective: Contact or atopic dermatitis; impetiginized eczema; nummular eczema; endogenous chronic infectious dermatitis; stasis dermatitis; pyoderma; nuchal eczema and chronic eczematoid otitis externa; acne urticata; localized or disseminated neurodermatitis; lichen simplex chronicus; anogenital pruritus (vulvae, scroti, ani); folliculitis; bacterial dermatoses; mycotic dermatoses such as tinea (capitis, cruris, corporis, pedis); monliasis; intertrigo. Final classification of the less-than-effective indications requires further investigation.

Apply to affected area(s) three to four times per day or as directed by a physician.


What interacts with Vytone?

Sorry No Records found


What are the warnings of Vytone?

Sorry No Records found


What are the precautions of Vytone?

Sorry No Records found


What are the side effects of Vytone?

The following local adverse reactions are reported infrequently with topical corticosteroids. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infections, skin atrophy, striae and miliaria.


What should I look out for while using Vytone?

This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product.

PRECAUTIONS: FOR EXTERNAL USE ONLY. NOT FOR OPHTHALMIC USE.

Information for Patients:

Iodoquinol may be absorbed through the skin and interfere with thyroid function tests. If such tests are contemplated, wait at least one month after discontinuance of therapy to perform these tests. The ferric chloride test for phenylketonuria (PKU) can yield a false positive result if iodoquinol is present in the diaper or urine. Prolonged use may result in overgrowth of non-susceptible organisms requiring appropriate therapy.

Carcinogenesis, Mutagenesis and Impairment of Fertility:

Pregnancy:

Category C.

Nursing Mothers:

Pediatric Use:


What might happen if I take too much Vytone?

Sorry No Records found


How should I store and handle Vytone?

This product is supplied in the following size(s): Carton, NDC 57893-302-30, containing 30 sachets (Net Wt. 2 g each). Each sachet is a unit of use - discard after opening. To reportManufactured for: Artesa Labs, LLC 13785 Research Blvd., Suite 125 Austin, TX 78750 827514 v3 Rev. 05/2017 This product is supplied in the following size(s): Carton, NDC 57893-302-30, containing 30 sachets (Net Wt. 2 g each). Each sachet is a unit of use - discard after opening. To reportManufactured for: Artesa Labs, LLC 13785 Research Blvd., Suite 125 Austin, TX 78750 827514 v3 Rev. 05/2017 This product is supplied in the following size(s): Carton, NDC 57893-302-30, containing 30 sachets (Net Wt. 2 g each). Each sachet is a unit of use - discard after opening. To reportManufactured for: Artesa Labs, LLC 13785 Research Blvd., Suite 125 Austin, TX 78750 827514 v3 Rev. 05/2017 This product is supplied in the following size(s): Carton, NDC 57893-302-30, containing 30 sachets (Net Wt. 2 g each). Each sachet is a unit of use - discard after opening. To reportManufactured for: Artesa Labs, LLC 13785 Research Blvd., Suite 125 Austin, TX 78750 827514 v3 Rev. 05/2017


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Hydrocortisone acetate has anti-inflammatory, antipruritic and vasoconstrictive properties. While the mechanism of anti-inflammatory activity is unclear, there is evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in humans. Iodoquinol has both antifungal and antibacterial properties.

Pharmacokinetics:

Non-Clinical Toxicology
This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product.

PRECAUTIONS: FOR EXTERNAL USE ONLY. NOT FOR OPHTHALMIC USE.

Information for Patients:

Iodoquinol may be absorbed through the skin and interfere with thyroid function tests. If such tests are contemplated, wait at least one month after discontinuance of therapy to perform these tests. The ferric chloride test for phenylketonuria (PKU) can yield a false positive result if iodoquinol is present in the diaper or urine. Prolonged use may result in overgrowth of non-susceptible organisms requiring appropriate therapy.

Carcinogenesis, Mutagenesis and Impairment of Fertility:

Pregnancy:

Category C.

Nursing Mothers:

Pediatric Use:

The following local adverse reactions are reported infrequently with topical corticosteroids. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infections, skin atrophy, striae and miliaria.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Review

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

Tips

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Interactions

Interactions

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