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Lidocaine, isopropyl alcohol

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Overview

What is Xryliderm?

Lidocaine patch 5% is comprised of an adhesive material containing 5% lidocaine, which is applied to a white non-woven polyethylene terephthalate (PET) material backing and covered with a transparent PET release liner. The release liner is removed prior to application to the skin. The size of the patch is 10 cm x 14 cm.

Lidocaine is chemically designated as acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl), has an octanol:water partition ratio of 43 at pH 7.4, and has the following structure:

Each adhesive patch contains 700 mg of lidocaine (50 mg per gram adhesive) in an aqueous base. It also contains the following inactive ingredients: glycerin, D-sorbitol, propylene glycol, polyvinyl alcohol, urea, sodium polyacrylate, carboxymethylcellulose sodium, gelatin, polyacrylic acid, kaolin, tartaric acid, dihydroxyaluminum aminoacetate, methylparaben, propylparaben, and edetate disodium.



What does Xryliderm look like?



What are the available doses of Xryliderm?

Sorry No records found.

What should I talk to my health care provider before I take Xryliderm?

Sorry No records found

How should I use Xryliderm?

Use as part of your daily cleansing routine

May be covered with a sterile bandage


What interacts with Xryliderm?

Sorry No Records found


What are the warnings of Xryliderm?

Sorry No Records found


What are the precautions of Xryliderm?

Sorry No Records found


What are the side effects of Xryliderm?

Sorry No records found


What should I look out for while using Xryliderm?

Lidocaine patch 5% is contraindicated in patients with a known history of sensitivity to local anesthetics of the amide type, or to any other component of the product.


What might happen if I take too much Xryliderm?

Lidocaine overdose from cutaneous absorption is rare, but could occur. If there is any suspicion of lidocaine overdose (see , ), drug blood concentration should be checked. The management of overdose includes close monitoring, supportive care, and symptomatic treatment. Dialysis is of negligible value in the treatment of acute overdose with lidocaine.

In the absence of massive topical overdose or oral ingestion, evaluation of symptoms of toxicity should include consideration of other etiologies for the clinical effects, or overdosage from other sources of lidocaine or other local anesthetics.

The oral LDof lidocaine HCl is 459 (346 to 773) mg/kg (as the salt) in non-fasted female rats and 214 (159 to 324) mg/kg (as the salt) in fasted female rats, which are equivalent to roughly 4000 mg and 2000 mg, respectively, in a 60 to 70 kg man based on the equivalent surface area dosage conversion factors between species.


How should I store and handle Xryliderm?

Store at 20°C to 25°C (68°F to 77°F) [see USP Controlled Room Temperature].Dispense in tight container as defined in the USP, with a child-resistant closure (as required).Store at 20°C to 25°C (68°F to 77°F) [see USP Controlled Room Temperature].Dispense in tight container as defined in the USP, with a child-resistant closure (as required).Lidocaine patch 5% is available as the following:Carton of 15 patches, NDC 59088-396-82Carton of 30 patches, NDC 59088-396-54Each patch is packaged into an individual child-resistant envelope.Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature].For more information, call Actavis at 1-800-272-5525.Manufactured by: Salt Lake City, UT 84108 USADistributed by:            San Fernando, CA 91340 USARev. 37780    02/16Lidocaine patch 5% is available as the following:Carton of 15 patches, NDC 59088-396-82Carton of 30 patches, NDC 59088-396-54Each patch is packaged into an individual child-resistant envelope.Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature].For more information, call Actavis at 1-800-272-5525.Manufactured by: Salt Lake City, UT 84108 USADistributed by:            San Fernando, CA 91340 USARev. 37780    02/16Lidocaine patch 5% is available as the following:Carton of 15 patches, NDC 59088-396-82Carton of 30 patches, NDC 59088-396-54Each patch is packaged into an individual child-resistant envelope.Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature].For more information, call Actavis at 1-800-272-5525.Manufactured by: Salt Lake City, UT 84108 USADistributed by:            San Fernando, CA 91340 USARev. 37780    02/16Lidocaine patch 5% is available as the following:Carton of 15 patches, NDC 59088-396-82Carton of 30 patches, NDC 59088-396-54Each patch is packaged into an individual child-resistant envelope.Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature].For more information, call Actavis at 1-800-272-5525.Manufactured by: Salt Lake City, UT 84108 USADistributed by:            San Fernando, CA 91340 USARev. 37780    02/16Lidocaine patch 5% is available as the following:Carton of 15 patches, NDC 59088-396-82Carton of 30 patches, NDC 59088-396-54Each patch is packaged into an individual child-resistant envelope.Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature].For more information, call Actavis at 1-800-272-5525.Manufactured by: Salt Lake City, UT 84108 USADistributed by:            San Fernando, CA 91340 USARev. 37780    02/16Lidocaine patch 5% is available as the following:Carton of 15 patches, NDC 59088-396-82Carton of 30 patches, NDC 59088-396-54Each patch is packaged into an individual child-resistant envelope.Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature].For more information, call Actavis at 1-800-272-5525.Manufactured by: Salt Lake City, UT 84108 USADistributed by:            San Fernando, CA 91340 USARev. 37780    02/16Lidocaine patch 5% is available as the following:Carton of 15 patches, NDC 59088-396-82Carton of 30 patches, NDC 59088-396-54Each patch is packaged into an individual child-resistant envelope.Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature].For more information, call Actavis at 1-800-272-5525.Manufactured by: Salt Lake City, UT 84108 USADistributed by:            San Fernando, CA 91340 USARev. 37780    02/16Lidocaine patch 5% is available as the following:Carton of 15 patches, NDC 59088-396-82Carton of 30 patches, NDC 59088-396-54Each patch is packaged into an individual child-resistant envelope.Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature].For more information, call Actavis at 1-800-272-5525.Manufactured by: Salt Lake City, UT 84108 USADistributed by:            San Fernando, CA 91340 USARev. 37780    02/16


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Lidocaine is an amide-type local anesthetic agent and is suggested to stabilize neuronal membranes by inhibiting the ionic fluxes required for the initiation and conduction of impulses.

The penetration of lidocaine into intact skin after application of lidocaine patch is sufficient to produce an analgesic effect, but less than the amount necessary to produce a complete sensory block.

Non-Clinical Toxicology
Lidocaine patch 5% is contraindicated in patients with a known history of sensitivity to local anesthetics of the amide type, or to any other component of the product.









Hepatic Disease:

Allergic Reactions:

Non-intact Skin:

External Heat Sources:

Eye Exposure:

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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